Amniotic fluid embolism

Morgan, M.

doi:10.1111/j.1365-2044.1979.tb04862.x

Cited by 221 publications

(168 citation statements)

References 105 publications

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“…Although three of these four women survived, a review of the English literature up to 1979 showed a survival rate of only 14 per cent. 3 In Morgan's review 3 of 272 cases, 90 per cent of cases occurred during labour; 28 per cent in tumultuous labour and 22 per cent in oxytocin stimulated labour. A small number complicated intrauterine deaths.…”

Section: Discussionmentioning

confidence: 99%

Amniotic fluid embolism: A report of four probable cases

Mainprize

Maltby

1986

Can Anaesth Soc J

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Section: Discussionmentioning

confidence: 99%

Amniotic fluid embolism: A report of four probable cases

Mainprize

Maltby

1986

Can Anaesth Soc J

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“…D Di is sc cu us ss si io on n DIC is a common complication of AFE and, in some cases, a bleeding diathesis may be the initial clinical presentation. 3 At present, the etiology remains obscure. Some authors have found substantial quantities of tissue factor in amniotic fluid and have suggested that this may be the triggering agent.…”

Section: Conclusion : Une Embolisation De L'artère Utérine Doit êTre mentioning

confidence: 99%

Two cases of hemorrhage secondary to amniotic fluid embolus managed with uterine artery embolization

Goldszmidt

Davies

2003

Can J Anesth/J Can Anesth

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P Pu ur rp po os se e: : To describe the anesthetic management of two cases of amniotic fluid embolus (AFE) and disseminated intravascular coagulation (DIC) who underwent bilateral uterine artery embolization to control their postpartum hemorrhage.C Cl li in ni ic ca al l f fe ea at tu ur re es s: : We report the clinical course and management of two women who suffered sudden cardiorespiratory events during labour. The first patient had a cardiac arrest whereas the second developed respiratory failure and altered neurological status. They were diagnosed as having had an AFE. Both of these events were accompanied by severe postpartum hemorrhage and DIC. They suffered prolonged bleeding and received massive transfusions. Successful management of hemorrhage was optimized by uterine artery embolization, thus avoiding ongoing problems with bleeding and possible hysterectomy. The role of uterine artery embolization is described, along with its advantages and anesthetic considerations.C Co on nc cl lu us si io on n: : Women with severe postpartum hemorrhage, with or without DIC, should be considered for uterine artery embolization. Objectif Conclusion : Une embolisation de l'artère utérine doit être envisagée chez des femmes qui subissent de sévères hémorragies postpartum, avec ou sans CIVD.MNIOTIC fluid embolus (AFE) is one of the most devastating complications of pregnancy. It can be neither predicted nor prevented and therefore remains one of the most feared entities among those caring for pregnant patients. Similar to other embolic phenomena, the clinical presentation and manifestations are quite variable. 1 The development of a consumptive coagulopathy, with or without clinically significant bleeding, appears to be inevitable in most, if not all, patients with AFE. 2 Despite appropriate management of the coagulopathy, the associated morbidity and mortality remain high. 1 The following report describes two patients with the clinical diagnosis of AFE in whom the successful management of the bleeding and coagulopathy were facilitated by uterine artery embolization.

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“…1,2 AFE is responsible for about 10% of all maternal deaths in the United States and is the most common cause of peripartum death. 1,2 Of the lethal dysrhythmias identified, 24% consisted of PEA, 22% of bradycardia, 17% of ventricular tachycardia/ventricular fibrillation, and 13% were asystole. 1 The patient in this case report had many of the signs and symptoms associated with AFE including cough, dyspnea, hypotension and cardiac arrest.…”

Section: Conclusion : On Sait Maintenant Que Les Caractéristiques Phmentioning

confidence: 99%

“…5 The overall incidence of AFE has been reported to range from 1 in 8,000 to 1 in 80,000 deliveries. 1,2 Although, other maternal catastrophes such as hemorrhage, pulmonary embolus and hypertensive disorders account for maternal deaths collectively, none are more devastating than AFE which has a maternal mortality rate that approaches 61 to 86%. 1,2 AFE is responsible for about 10% of all maternal deaths in the United States and is the most common cause of peripartum death.…”

Section: Conclusion : On Sait Maintenant Que Les Caractéristiques Phmentioning

confidence: 99%

“…1,2 AFE has a variable presentation, ranging from mild degrees of organ dysfunction to cardiovascular collapse, coagulopathy and death. 1,2 AFE usually presents at term during labour. 3 In this report, we present a patient in her second trimester of pregnancy who developed sudden hypoxic respiratory failure followed by cardiopulmonary arrest and coagulopathy following dilatation and evacuation (D & E) for intra-uterine fetal demise.…”

Section: Conclusion : On Sait Maintenant Que Les Caractéristiques Phmentioning

confidence: 99%

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Embolie amniotique lors d’une interruption de grossesse au deuxième trimestre : exposé d’un cas

Ray

Vallejo

Creinin

et al. 2004

Can J Anesth/J Can Anesth

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P Pu ur rp po os se e: : Describe the diagnosis, clinical features, pathophysiology, treatment and anesthetic management of amniotic fluid embolism (AFE) in a patient undergoing second trimester pregnancy termination.C Cl li in ni ic ca al l f fe ea at tu ur re es s: : A 30-yr-old gravida 2, para 1, woman was admitted for a dilatation and evacuation procedure for underlying intra-uterine fetal demise in her second trimester of pregnancy. Hypotension, shock, respiratory arrest, pulseless electrical activity, hemorrhage, disseminated intravascular coagulopathy, requiring cardiopulmonary resuscitation and blood transfusion complicated her intraoperative care. AFE was considered the most likely cause of this intraoperative event.C Co on nc cl lu us si io on ns s: : It is now recognized that the pathophysiological features of AFE are similar to a type-1 hypersensitivity reaction ranging from mild systemic reaction to anaphylaxis and shock. AFE has a high maternal and fetal morbidity and mortality rate, requiring prompt recognition and treatment. In patients with cardiovascular instability, the treatment of AFE is similar to anaphylaxis requiring aggressive fluid hydration, cardiopulmonary resuscitation, administration of blood products and the use of vasopressors. MNIOTIC fluid embolism (AFE) is a rare life-threatening complication unique to pregnancy. AFE has a mortality rate of 61 to 86% and accounts for approximately 10% of all maternal deaths in the United States. 1,2 AFE has a variable presentation, ranging from mild degrees of organ dysfunction to cardiovascular collapse, coagulopathy and death. 1,2 AFE usually presents at term during labour. 3 In this report, we present a patient in her second trimester of pregnancy who developed sudden hypoxic respiratory failure followed by cardiopulmonary arrest and coagulopathy following dilatation and evacuation (D & E) for intra-uterine fetal demise. Objectif

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Amniotic fluid embolism

Abstract: Table 1. Composition of amniotic fluid (after Ostergard ") Electrolytes Nitrogenous Amino acids, urea, uric Glucose, vitamins, enzymes, steroid hormones Lipids Fatty acids, phospholipids, Prostaglandins

Cited by 221 publications

References 105 publications

Amniotic fluid embolism: A report of four probable cases

Amniotic fluid embolism: A report of four probable cases

Two cases of hemorrhage secondary to amniotic fluid embolus managed with uterine artery embolization

Embolie amniotique lors d’une interruption de grossesse au deuxième trimestre : exposé d’un cas

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