Amniotic Fluid Surface Tension during Pregnancy

Rubaltelli, Firmino F.; Rondinelli, M; Zorzi, C; Saia, Sergio O.

doi:10.1159/000240855

Neonatology

1976

DOI: 10.1159/000240855

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Amniotic Fluid Surface Tension during Pregnancy

Firmino F. Rubaltelli¹,

M Rondinelli²,

C Zorzi³

et al.

Abstract: A good correlation between the amniotic fluid surface tension and gestational age was found in 51 amniotic fluid samples from normal pregnancies. The samples were obtained between the 20th and 43rd week of gestation. A good relation also exists between amniotic fluid lecithin concentration and fluid surface tension, and between said surface tension and the foam test carried out according to Clements et al. (4).

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1982

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Methods of Evaluating Fetal Lung Maturity

Brown

Duck-Chong

1982

CRC Critical Reviews in Clinical Laboratory Sciences

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Respiratory distress syndrome occurs in infants born with immature lungs. The immature fetal lung lacks an adequate supply of surfactant, a phospholipid-rich substance which is produced in the type II cells of the alveolar epithelium. In the fetus, surfactant is secreted into the potential air spaces of the lung and passes into the amniotic fluid as gestation proceeds. It is now clear that most methods currently in use for assessing fetal lung maturity depend on the detection of a sudden release of surfactant into the amniotic fluid as the lung reaches a critical stage of maturity. These methods, which include the lecithin/sphingomyelin ratio, the lung profile, total phospholipid or lecithin concentration, fluorescence depolarization, lamellar body phospholipid concentration, and the "shake" test, are reviewed in the light of recent understanding of the nature of surfactant. In assessing each method, we have examined possible sources of error in performing the test in the laboratory, factors which could theoretically limit its ability to reflect the state of fetal lung maturity and current information regarding its reliability, in terms of clinical performance. Guidelines for future research in this area are also suggested.

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Methods of Evaluating Fetal Lung Maturity

Brown

Duck-Chong

1982

CRC Critical Reviews in Clinical Laboratory Sciences

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Amniotic Fluid Surface Tension during Pregnancy

Cited by 1 publication

References 4 publications

Methods of Evaluating Fetal Lung Maturity

Methods of Evaluating Fetal Lung Maturity

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