Amniotic membrane harvesting during COVID-19 pandemic

Biological importance of human amniotic membrane in tissue engineering and regenerative medicine

“…The source of hAM collection, whether after vaginal delivery or via cesarean section, influence its physiology, integrity, availability, and growth factor content and has a contamination risk. The hAM donors should be screened to minimize infectious disease transmission, particularly after the COVID-19 pandemic owing to the concerns about vertical transmission [ 94 ]. After collection, the placenta is packaged in a sterile container and transferred to the laboratory for processing.…”

Applications of the amniotic membrane in tissue engineering and regeneration: the hundred-year challenge

“…The source of the Amnio-M source, whether after natural delivery or via Cesarean section, was found to impact its physiology, integrity, growth factors content, and availability. The Amnio-M donor should be screened to avoid transmission of infectious diseases [ 136 ], and especially after the COVID-19 pandemic due to fears of vertical transmission [ 137 ]. Litwiniuk, Radowicka [ 138 ] reported that Cesarean section-derived cervical portion of the Amnio-M stimulated the proliferation of keratinocytes more than that of fibroblasts.…”

Implications of SARS CoV-2 positivity in amniotic membranes for ophthalmologists

“…We read with interest the article by Seah et al [1] and correspondence thereof by Yeung [2] regarding the potential dangers of COVID-19 in ophthalmologic practice. While the former highlighted the importance of human secretions like tears as a potential source of transmission of the virus, the latter explored the possibility of SARS-CoV-2 in amniotic membrane grafts.…”