Amoxicillin-degradation products formed under controlled environmental conditions: Identification and determination in the aquatic environment

Gozlan, Igal; Rotstein, Adi; Avisar, Dror

doi:10.1016/j.chemosphere.2013.01.095

Cited by 148 publications

(84 citation statements)

References 33 publications

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“…However, highly mobile contaminants and/or degradation products thereof are not of less concern, since due to leaching processes can contaminate groundwater. For instance, amoxicillin degradation products were observed to contaminate groundwater in an agricultural field irrigated with wastewater (Gozlan et al, 2013).…”

Section: Contaminantsmentioning

confidence: 99%

Wastewater reuse in irrigation: A microbiological perspective on implications in soil fertility and human and environmental health

Becerra-Castro

Lopes

Vaz‐Moreira

et al. 2015

Environment International

430

211

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The reuse of treated wastewater, in particular for irrigation, is an increasingly common practice, encouraged by governments and official entities worldwide. Irrigation with wastewater may have implications at two different levels: alter the physicochemical and microbiological properties of the soil and/or introduce and contribute to the accumulation of chemical and biological contaminants in soil. The first may affect soil productivity and fertility; the second may pose serious risks to the human and environmental health. The sustainable wastewater reuse in agriculture should prevent both types of effects, requiring a holistic and integrated risk assessment. In this article we critically review possible effects of irrigation with treated wastewater, with special emphasis on soil microbiota. The maintenance of a rich and diversified autochthonous soil microbiota and the use of treated wastewater with minimal levels of potential soil contaminants are proposed as sine qua non conditions to achieve a sustainable wastewater reuse for irrigation.

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Section: Contaminantsmentioning

confidence: 99%

Wastewater reuse in irrigation: A microbiological perspective on implications in soil fertility and human and environmental health

Becerra-Castro

Lopes

Vaz‐Moreira

et al. 2015

Environment International

430

211

View full text Add to dashboard Cite

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“…At high pH, the lone pair electrons on the amine group of the AMX-penicilloic acid are available for nucleophilic attack on the carbonyl group to yield a six membered stable diketopiperazine ring and the AMX diketopiperazine degradation product [89]. In the other hand, at low pH, the AMX-penicilloic acid suffers a decarboxylation process yielding the AMX penicilloic acid degradation product [89].…”

Section: Environmental Degradation Of Amoxicillinmentioning

confidence: 99%

Amoxicillin in the Aquatic Environment, Its Fate and Environmental Risk

Elizalde-Velázquez¹,

Gómez-Oliván²,

Galár-Martínez³

et al. 2016

Environmental Health Risk - Hazardous Factors to Living Species

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Amoxicillin is a broad-spectrum antibiotic widely used for treating both human and animal diseases, and it belongs to a group that are excreted unchanged within urine and faeces; therefore, it is possible to find traces of this drug or its degradation products in environmental water bodies. In water, it is rapidly degraded by biotic and abiotic factors, yielding different intermediate products; these are suspected of being more resistant to degradation, and potentially more toxic, than the parent compound. In the water bodies, these compounds may produce toxic effects on the aquatic organisms from different trophic levels and produce an ecological imbalance. Amoxicillin may bioaccumulate in fish muscle tissues, with the possibility of the occurrence of these drugs in food, leading to a passive consumption of this antibiotic resulting in undesirable effects on consumer health such as immunoallergic responses. However, the main problem related with the presence of this antimicrobial compounds in fish tissues is the possibility of inducing bacterial resistance genes. At present, the available scientific knowledge is less than what is needed to fully assess the risks that amoxicillin pose to the environment, and it is still necessary to conduct large amount of research works before a thorough understanding of this severe environmental issue.

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“…For example, in some amoxicillin-degradation products, it was observed that high-mobility compounds polluted the groundwater of wastewater-irrigated agricultural fields [133]. Another study concluded, after discovering low retention rates for ibuprofen in soils, that this compound has a high potential to percolate through soil and pollute groundwater sources [145].…”

Section: Limitations Associated With Agricultural Wastewater Reusementioning

confidence: 99%

Wastewater Reuse in Agriculture: A Review about Its Limitations and Benefits

2017

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For centuries, wastewater has been improperly used in agriculture, presenting potential risks to public health and the environment. In the context of scientific development, and confronted by an increasing water crisis, wastewater reuse merits consideration because the practice helps decrease water use pressure and moderates water pollution. Thus, this article presents a literature review that addresses the effects, both positive and negative, of wastewater use in agriculture, emphasizing the effects on the soil environment. The literature review reveals that, until the 1990s, research studies promoted the use of wastewater for irrigation purposes from a treatment approach, while proposing "end of pipe" conventional solutions. However, more recent research studies (2012)(2013)(2014)(2015)(2016) reveal that agricultural reuse significantly affects soil texture properties, while also causing possible alterations of the biomass and microbiota. In addition, research in this period has been oriented to the quantitative evaluation of microbiological risk.

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Amoxicillin-degradation products formed under controlled environmental conditions: Identification and determination in the aquatic environment

Cited by 148 publications

References 33 publications

Wastewater reuse in irrigation: A microbiological perspective on implications in soil fertility and human and environmental health

Wastewater reuse in irrigation: A microbiological perspective on implications in soil fertility and human and environmental health

Amoxicillin in the Aquatic Environment, Its Fate and Environmental Risk

Wastewater Reuse in Agriculture: A Review about Its Limitations and Benefits

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