“…11,12) Moreover, drug targeting can also be achieved by using drug vehicles sensitive to the surrounding enzymes, temperature or pH. [13][14][15] Recently, several studies reported [16][17][18][19][20][21][22][23] that introduction of a suitable substituent (e.g., glucose, galactose, arbutin, hydroquinone α-glycoside, porphyrin, or β-carboline) to the rim of α-and β-CDs, can enhance the binding affinity towards DOX through cooperative interactions between the CD's cavity and guest molecules. Although, α-and β-CD are the most exploited CDs, 24) little has been published on γ-CD (1) as targeted drug delivery system.…”