2012
DOI: 10.4236/abb.2012.33027
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<i>Sulfotransferase</i> 1A1 G638A polymorphism, cigarette smoking and bladder cancer risk in Taiwan

Abstract: Cigarette smoking is a major risk factor for bladder cancer (BC). Sulfotransferase 1A1 (SULT1A1), a phase II enzyme, plays an important role in the metabolism of several carcinogens contained in cigarettes. The aim of this study was to investigate the relationship between SULT1A1 G638A polymorphism, cigarette smoking and bladder cancer risk in Taiwan. A total of 150 BC patients and 150 cancer-free controls were recruited from February 2002 to February 2009. Genotyping of the SULT1A1 G638A polymerphism was dete… Show more

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