AmpC β-lactamase Production in Pseudomonas aeruginosa: A Threat

Agrawal, Anshu; Srivastava, Namita; Kumar, Dharmendra; mi, Rash; Bhati, N. N.

doi:10.20546/ijcmas.2017.612.243

Int.J.Curr.Microbiol.App.Sci

2017

DOI: 10.20546/ijcmas.2017.612.243

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AmpC β-lactamase Production in Pseudomonas aeruginosa: A Threat

Anshu Agrawal¹,

Namita Srivastava²,

Dharmendra Kumar³

et al.

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2024

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Cited by 2 publications

References 15 publications

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Pseudomonas aeruginosa from a Tertiary Teaching Hospital: A Study of AmpC and Biofilm-producing Clinical Isolates

Yadav,

Pawar,

Kakade

et al. 2024

Journal of Datta Meghe Institute of Medical Sciences University

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Introduction: Opportunistic Pseudomonas aeruginosa is one of the most prevalent bacteria with a broad spectrum of human-associated infections. The World Health Organization (WHO) claims that Pseudomonas aeruginosa infection is a typical healthcare-associated disease of critical or high concern. It is well known for being inherently resistant to many antibiotics and has the ability to produce biofilm. In the present study, we aimed to investigate P. aeruginosa with reference to biofilm and AmpC β-lactamases producing isolates in a tertiary care hospital. Materials and Methods: An observational cross-sectional study was performed at the Department of Microbiology, KIMS, KVV, Karad, and Krishna Hospital & Medical Research Center, Karad. (KH & MRC). A total of 180 isolates were subjected to this test to find out which produced the AmpC β -lactamase enzyme by the cefoxitin-cloxacillin double-disc synergy test method and biofilm production by tissue culture plate assay method. Results: Our study found a total of 97 isolates (53.89%) of AmpC production and biofilm production accounted for 151 (83.89%). Conclusion: AmpC- beta-lactamases are responsible for increasing the resistance of P. aeruginosa to several beta-lactam antibiotics and this study also showed that the clinical isolates of P. aeruginosa had a higher propensity to form biofilm and that there was a direct association between biofilm formation and antibiotic resistance.

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Pseudomonas aeruginosa from a Tertiary Teaching Hospital: A Study of AmpC and Biofilm-producing Clinical Isolates

Yadav,

Pawar,

Kakade

et al. 2024

Journal of Datta Meghe Institute of Medical Sciences University

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Phenotypic and Genotypic Characterization of AmpC Beta-Lactamase in Clinical Isolates of Pseudomonas aeruginosa Findings From a Tertiary Care Hospital

Yadav,

Pawar,

Datkhile

et al. 2024

Cureus

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AmpC β-lactamase Production in Pseudomonas aeruginosa: A Threat

Cited by 2 publications

References 15 publications

Pseudomonas aeruginosa from a Tertiary Teaching Hospital: A Study of AmpC and Biofilm-producing Clinical Isolates

Pseudomonas aeruginosa from a Tertiary Teaching Hospital: A Study of AmpC and Biofilm-producing Clinical Isolates

Phenotypic and Genotypic Characterization of AmpC Beta-Lactamase in Clinical Isolates of Pseudomonas aeruginosa Findings From a Tertiary Care Hospital

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