Amperometric and voltammetric detection for capillary electrophoresis

Abstract

The focus of this article is amperometric and voltammetric detection coupled with capillary electrophoresis. Fundamental concepts and progress in the field of capillary electrophoresis with electrochemical detection (CEEC) that have occurred within the past three years, including new methodologies and unique applications, are highlighted. This review contains 95 references.

Determination of Three Bioactive Constituents in Moutan Cortex by Capillary Electrophoresis with Electrochemical Detection

“…12,13 Electrochemical detection (ECD) typically operated in the amperometric mode can be coupled with CE to provide high sensitivity and selectivity for the determination of electroactive substances. [14][15][16] It is of high importance to control the quality of herbal drugs based on their active constituents and some co-existent substances. In 2000, the U.S. Food and Drug Administration (FDA) published a draft of Guidance for Industry Botanical Drug Products.…”

Recent developments in electrochemical flow detections—A review

“…Besides a large number of original papers on this subject, reaching about 200, several reviews on application of electrochemical detection in CE have been published in recent years, e.g. [157][158][159][160], as well as on more detailed subjects such as coupling of CE and pulsed electrochemical detection [161], or on carbon nanotubes and diamond as electrochemical detectors in microchip and conventional CE [162]. Like in the previous chapter, development trends observed in about recent 10 years will be presented based on original papers selected from the literature, with particular attention paid to works where application of electrochemical detection allows obtaining very low detection limits.…”

Bioanalytical profile of the l-arginine/nitric oxide pathway and its evaluation by capillary electrophoresis

“…CEECD has rapidly expanded to an attractive alternative of technologically more changing UV/LIF and CD/CCD-based technique in both conventional fused silica capillary assay and microchip-based frameworks; see for example refs. [330] and [331][332][333], respectively.…”