Amperometric Biosensor for Diagnosis of Disease

Ferreira, Antonio Aparecido Pupim; Uliana, Carolina Venturini; Castilho, Michelle de Souza; Pesquero, Naira Canaverolo; Foguel, Marcos Vinicius; Santos, Glauco Pilon dos; Fugivara, Cecilio Sadao; Benedetti, Assis Vicente; Yamanaka, Hideko

doi:10.5772/53656

Cited by 8 publications

(4 citation statements)

References 107 publications

(111 reference statements)

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“…The regeneration observed between measurements should be particularly careful, as it is a drawback of the technique. Nowadays, disposable printed electrodes are used instead, because they are cheap and can be produced in large scale [142,143]. Amperometric sensors have been successfully tested for HT-2 toxin, T-2 toxin, and AFM1, in human urine [113], for OTA in red wine [126] and for ZEN in corn and corn products [134,135].…”

Section: Amperometric Sensorsmentioning

confidence: 99%

Advances in Analysis and Detection of Major Mycotoxins in Foods

Agriopoulou

Stamatelopoulou

Varzakas

2020

Foods

140

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Mycotoxins are the most widely studied biological toxins, which contaminate foods at very low concentrations. This review describes the emerging extraction techniques and the current and alternatives analytical techniques and methods that have been used to successfully detect and identify important mycotoxins. Some of them have proven to be particularly effective in not only the detection of mycotoxins, but also in detecting mycotoxin-producing fungi. Chromatographic techniques such as high-performance liquid chromatography coupled with various detectors like fluorescence, diode array, UV, liquid chromatography coupled with mass spectrometry, and liquid chromatography-tandem mass spectrometry, have been powerful tools for analyzing and detecting major mycotoxins. Recent progress of the development of rapid immunoaffinity-based detection techniques such as immunoassays and biosensors, as well as emerging technologies like proteomic and genomic methods, molecular techniques, electronic nose, aggregation-induced emission dye, quantitative NMR and hyperspectral imaging for the detection of mycotoxins in foods, have also been presented.

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Section: Amperometric Sensorsmentioning

confidence: 99%

Advances in Analysis and Detection of Major Mycotoxins in Foods

Agriopoulou

Stamatelopoulou

Varzakas

2020

Foods

140

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“…These devices offer smart routes for relating the DNA recognition element to the signal-transduction processes. Biosensors based on DNA hybridization depend on the generation of an electrical signal from the DNA base-pair recognition event [ 44 , 45 , 46 ]. Such a hybridization process is commonly detected via increased current signal of an electroactive indicator.…”

Section: Dna-based Nanobiosensors For Detection Of Infectious Disementioning

confidence: 99%

DNA-Based Nanobiosensors as an Emerging Platform for Detection of Disease

Abu‐Salah

Zourob

Mouffouk

et al. 2015

Sensors

118

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Detection of disease at an early stage is one of the biggest challenges in medicine. Different disciplines of science are working together in this regard. The goal of nanodiagnostics is to provide more accurate tools for earlier diagnosis, to reduce cost and to simplify healthcare delivery of effective and personalized medicine, especially with regard to chronic diseases (e.g., diabetes and cardiovascular diseases) that have high healthcare costs. Up-to-date results suggest that DNA-based nanobiosensors could be used effectively to provide simple, fast, cost-effective, sensitive and specific detection of some genetic, cancer, and infectious diseases. In addition, they could potentially be used as a platform to detect immunodeficiency, and neurological and other diseases. This review examines different types of DNA-based nanobiosensors, the basic principles upon which they are based and their advantages and potential in diagnosis of acute and chronic diseases. We discuss recent trends and applications of new strategies for DNA-based nanobiosensors, and emphasize the challenges in translating basic research to the clinical laboratory.

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“…Due to their sensitivity, selectivity, and ease of operation, amperometric biosensors find widespread applications in medical diagnostics, environmental monitoring, food testing, and the detection of drugs. 3 Quantitative determination of enzyme activity before and after interaction with a particular substrate is crucial for the development of these biosensors. 4 Yoetz-Kopelman et al developed a model that describes suspended vs. immobilized whole-cell amperometric biosensors.…”

Section: ■ Introductionmentioning

confidence: 99%

A Theoretical Approach to Understand the Nonlinear Processes in Enzymatic Electrochemical Biosensors

Annamalai,

Balu,

Alwarappan

et al. 2024

J. Phys. Chem. B

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Amperometric Biosensor for Diagnosis of Disease

Cited by 8 publications

References 107 publications

Advances in Analysis and Detection of Major Mycotoxins in Foods

Advances in Analysis and Detection of Major Mycotoxins in Foods

DNA-Based Nanobiosensors as an Emerging Platform for Detection of Disease

A Theoretical Approach to Understand the Nonlinear Processes in Enzymatic Electrochemical Biosensors

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