Amphiphilic metallosurfactants as potential scaffolds for facile fabrication of PdO-NiO nanocomposites for environmentally benign synthesis of xanthene derivatives

A sustainable gateway to access 1,8-dioxo-octahydroxanthene scaffoldsviaa surface-engineered halloysite-based magnetically responsive catalyst

“…On the basis of previous literature reports and the results of the control experiments conducted, we propose a plausible mechanistic pathway for the Cu( ii )@DCH@CPTMS@MHNTs-catalyzed one-pot synthesis of xanthene motifs, as represented in Scheme 3. 75–77 The first step involves the activation of the carbonyl group of the aldehyde moiety by the synthesized Cu( ii )@DCH@CPTMS@MHNTs, which enhances its susceptibility towards nucleophilic attack by the cyclohexanedione motif, leading to the formation of complex A. In the next step, the loss of a water molecule from complex A gives complex B which undergoes a Michael addition with the second molecule of cyclohexanedione and furnishes complex C. After this, the intramolecular cyclization of complex C leads to the generation of complex D, which subsequently loses another molecule of water to afford the desired xanthene scaffold as well as the regenerated Cu( ii )@DCH@CPTMS@MHNTs.…”

“…1,8-Dioxo-octahydroxanthenes belonging to a significant class of aromatic oxygen-containing heterocycles have been gaining huge prominence in medicinal chemistry due to their diversified pharmacological properties. 30,31 Xanthene derivatives possess a broad array of biological and pharmaceutical activities, like analgesic, antiviral, anticancer, antibacterial and anti-inflammatory activities. 32–34 Further, these motifs have been widely exploited as antagonists in photodynamic therapy, fluorescent dyes, pH-sensitive fluorescent materials for visualization of biomolecules, and also utilized in laser technology.…”

Metallo-Liposomes Derived from the [Ru(bpy)3]2+ Complex as Nanocarriers of Therapeutic Agents

“…Figure 5A shows the trend observed in EI with the liposome concentration. A K app value of 2.6 × 10 4 g −1 mL −1 was obtained at α = 0.32 from a non-linear fit by using Equation (7). This value agrees with those obtained for metallo-liposomes formed by the doublechained RuC11C11 (or RuC19C19) and 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine (DOPE) [25], confirming that the binding of the Ru-based liposomes to ct-DNA is mainly due to electrostatic interactions between the cationic head groups of the ruthenium surfactants and the phosphate groups of the nucleic acid.…”

“…Metallosurfactants have also been used as potential precursors in new synthetic methods, as antimicrobial and antibactericidal agents, and as contrast agents in diagnostic tests, etc. [7][8][9][10].…”

Supramolecular grafting and stabilization of manganese complex on kryptofix23 modified Fe3O4@carbon nanosphere: as highly efficient, reusable, and clean nanocatalyst for xanthene’s unusual coupling

“…In this work, we prepared to functionalize Fe 3 O 4 with glucose. Xanthenes; as a fascinating type of oxygen-containing compounds [24], have attracted a great notice for their vast range of medical and biological properties [25] such as antiviral [26], antibacterial [27] and anti-in ammatory operations [28];…”