Amphiphilic poly(2-oxazoline) copolymers as self-assembled carriers for drug delivery applications

Poly(2‐oxazoline)s: A comprehensive overview of polymer structures and their physical properties

“…In the last few years PAOx have emerged as materials for biomedical and pharmaceutical applications, such as polymer−drug and polymer−protein conjugates, self‐assembled carriers for drug delivery, solid dispersions, hydrogels, antibiofouling and antimicrobial surfaces, and wound healing . In the 50 years since the first reports on PAOx the CROP of more than a hundred different 2‐oxazolines has been reported.…”

“…In the last decade PAOx have received increasing interest, especially for biomedical applications. Several reviews on this topic have recently been published providing an excellent overview of the current state of the art . Even though the application potential of PAOx is tremendous and has been the focus of many review articles, it is relatively difficult to get a complete overview of the different PAOx structures that have been reported as well as a systematic insight into the properties of the different PAOx.…”

Self‐Assembly of Azobenzene Derivatives into Organogels and Photoresponsive Liquid Crystals

“…1 The residue was purified by using as ilica gel column, eluting with CH 2 Cl 2 to afford an orange solid (0.43 g, 48 %).…”

“…[1][2][3][4][5][6] The controlo f weak and multiple noncovalent interactions, such as hydrogen bonding, p-p stacking, and van der Waals forces, at the molecular level, is critical in regulating the nano-to micro-size architectures, chromophore packing, and opticalp roperties. [1][2][3][4][5][6] The controlo f weak and multiple noncovalent interactions, such as hydrogen bonding, p-p stacking, and van der Waals forces, at the molecular level, is critical in regulating the nano-to micro-size architectures, chromophore packing, and opticalp roperties.…”

Acyl guanidine functional poly(2‐oxazoline)s as reactive intermediates and stimuli‐responsive materials

“…Poly(2‐alkyl/aryl‐2‐oxazoline)s (PAOx's) are a polymer class possessing a large structural versatility, allowing straightforward tuning of the polymer properties and functionality . This appealing feature and their excellent physicochemical stability in combination with biocompatibility have led to their rising popularity as a biomedical material, for example, polymer–drug conjugates, tissue engineering, matrix excipient, and controlled drug release . Within most of these applications, postpolymerization modification reactions play a central role in the synthesis of functional polymers, enabling to overcome the limitations of the cationic ring‐opening polymerization (CROP).…”