Amphotericin B

Bernardo, José F.; Sabra, Ramzi; Vyas, Subhash J.; Branch, Robert A.

doi:10.1007/1-4020-2586-6_10

Clinical Nephrotoxins 2003

DOI: 10.1007/1-4020-2586-6_10

|View full text |Cite

Amphotericin B

José F. Bernardo

Ramzi Sabra

Subhash J. Vyas

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2007

2016

Publication Types

Select...

Article4

Relationship

Self Cite0

Independent4

Authors

Journals

Cited by 4 publications

References 126 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Synthesis and antifungal activity of N-benzyl derivatives of amphotericin B

Belakhov

Shenin

2007

Pharm Chem J

View full text Add to dashboard Cite

N-Benzyl derivatives of the polyene macrolide antibiotic amphotericin B were formed by reacting it with benzaldehydes and cyanoborohydride under reductive amination conditions. The physicochemical and biological properties of the resulting amphotericin B derivatives were studied. The N-benzyl derivatives of amphotericin B had high antifungal activity against a broad range of test cultures. Biological studies found that the acute toxicity of the amphotericin B derivatives was three times less than for the starting antibiotic.

show abstract

Synthesis and antifungal activity of N-benzyl derivatives of amphotericin B

Belakhov

Shenin

2007

Pharm Chem J

View full text Add to dashboard Cite

show abstract

Synthesis and antifungal activity of N-aryl-substituted pimaricin derivatives

2010

View full text Add to dashboard Cite

Reactions of the tetraene macrolide antibiotic pimaricin with 1-fluorobenzenes resulted in the formation of N-aryl-substituted derivatives. The physicochemical and biological properties of the synthesized pimaricin derivatives were studied. The N-aryl-substituted pimaricin derivatives showed high antifungal activity against a broad spectrum of test cultures. The biological studies showed that the acute toxicity (LD 50 ) of the obtained pimaricin derivatives was half that of the starting antibiotic.

show abstract

Synthesis and Antifungal and Antiviral Activity of N-Benzyl Derivatives of the Tetraene Macrolide Antibiotic Lucensomycin

et al. 2016

View full text Add to dashboard Cite

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Amphotericin B

Cited by 4 publications

References 126 publications

Synthesis and antifungal activity of N-benzyl derivatives of amphotericin B

Synthesis and antifungal activity of N-benzyl derivatives of amphotericin B

Synthesis and antifungal activity of N-aryl-substituted pimaricin derivatives

Synthesis and Antifungal and Antiviral Activity of N-Benzyl Derivatives of the Tetraene Macrolide Antibiotic Lucensomycin

Contact Info

Product

Resources

About