Ampicillin Nephropathy

Tannenberg, Alf M.

doi:10.1001/jama.1971.03190160097035

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Drug-hapten Conjugates As Nephritogenic Antigens1

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1976

2008

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Cited by 28 publications

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“…Drugs or their metabolites serving as a hapten in the interstitium come from three lines of evidence. There are increased serum IgE titers in some patients with sulfonamide-induced TIN (199), and circulating anti-ampicillin antibodies have been found in two cases (199,373). In a case report of penicillin (PCN)-induced TIN, PCN was detected along the TBM (65); however, PCN can also be detected along TBM in patients receiving PCN who do not have TIN.…”

Section: Drug-hapten Conjugates As Nephritogenic Antigensmentioning

confidence: 99%