Ampicillin/sulbactam for children hospitalized with community-acquired pneumonia

Tapisiz, Anıl; Özdemir, Halil; Çıftçı, Ergın; Belet, Nurşen; İnce, Erdal; Doğru, Ülker

doi:10.1007/s10156-011-0208-3

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…In a large multicenter study of children unvaccinated against Streptococcus pneumoniae hospitalized with WHO-defined severe pneumonia, Ferrero et al [52] found that pleural effusions were associated with pneumococcal bacteremia (OR, 3.1; 95% CI, 1.23-7.98). In children hospitalized with pneumonia, pleural effusions were the factors most associated with empiric parenteral ampicillin/ sulbactam treatment failure (aOR, 5.74; 95% CI, 2.17-15.15) [53]. Complex loculated effusions contribute to treatment failure with conservative measures leading to increased LOS and need for surgical interventions [54,55].…”

Section: Radiographic Factorsmentioning

confidence: 99%

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Dean

Florin

2018

Journal of the Pediatric Infectious Diseases Society

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Community-acquired pneumonia in children is associated with significant morbidity and mortality; however, data are limited in predicting which children will have negative outcomes, including clinical deterioration, severe disease, or development of complications. The Pediatric Infectious Diseases Society/Infectious Diseases Society of America (PIDS/IDSA) pediatric pneumonia guideline includes criteria that were modified from adult criteria and define pneumonia severity to assist with resource allocation and site-of-care decision-making. However, the PIDS/IDSA criteria have not been formally developed or validated in children. Definitions for mild, moderate, and severe pneumonia also vary across the literature, further complicating the development of standardized severity criteria. This systematic review summarizes (1) the current state of the evidence for defining and predicting pneumonia severity in children as well as (2) emerging evidence focused on risk stratification of children with pneumonia.

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Section: Radiographic Factorsmentioning

confidence: 99%

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Dean

Florin

2018

Journal of the Pediatric Infectious Diseases Society

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Fabrication of ampicillin/starch/polymer composite nanofibers with controlled drug release properties by electrospinning

Tang

Zhao

Chen

et al. 2015

J Sol-Gel Sci Technol

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What are the risk factors for death among children with pneumonia in low- and middle-income countries? A systematic review

et al. 2023

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This review aimed to identify clinical, demographic, and investigation findings that are associated with treatment failure or mortality in children (aged two months to nine years) with pneumonia in LMICs. METHODSWe conducted a systematic search of medical databases MEDLINE, EMBASE, and PubMed (for recent studies not yet indexed on MEDLINE) for studies reporting on factors associated with child pneumonia mortality (August 30, 2020). We mapped search terms to medical subject headings where possible, using Boolean operators to combine searches into our final systematic search query. We used synonyms of "pneumonia", "mortality", and "child" to target our search strategy, with oversight from an experienced Health Service Librarian to ensure all relevant papers were identified. We also searched reference lists of all included references for eligible studies. Additional methodological detail, including the Medline search strategy, information sources and data collection processes are included in Text S1 in the Online Supplementary Document. Assessment of study eligibilityWe included observational and interventional studies from LMICs involving children aged 28 days to nine years with pneumonia and reporting data on risk factors for death. We focussed on studies published since 2010 to reflect current aetiology and diagnostic / treatment approaches and limited to English language. We included studies involving children older than five years of age as this is an important neglected child population but expected most studies to focus on the traditional under five-year population. Two reviewers (CW and MB) independently screened the titles and abstracts of all returned studies, obtained full text for studies that were screened in by either reviewer, then independently assessed them for inclusion. We resolved disagreements by discussion and, where appropriate, review by a third reviewer (HG). None of the reviewers were blind to the journal titles, study authors, or affiliated institutions.

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Ampicillin/sulbactam for children hospitalized with community-acquired pneumonia

Cited by 4 publications

References 26 publications

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Factors Associated With Pneumonia Severity in Children: A Systematic Review

Fabrication of ampicillin/starch/polymer composite nanofibers with controlled drug release properties by electrospinning

What are the risk factors for death among children with pneumonia in low- and middle-income countries? A systematic review

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