Amplified Photoacoustic Signal and Enhanced Photothermal Conversion of Polydopamine-Coated Gold Nanobipyramids for Phototheranostics and Synergistic Chemotherapy

Liu, Yanhong; Li, Ziwei; Yin, Zhibin; Zhang, Hongxin; Gao, Yang; Huo, Guoyan; Wu, Aiguo; Zeng, Leyong

doi:10.1021/acsami.9b22979

Cited by 73 publications

(51 citation statements)

References 57 publications

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“…Light-responsive nanoprobes for safe and efficient phototheranostics consisting of PDA-coated gold nanobipyramids conjugated with doxorubicin drug were successfully synthesised by Liu et al [96]. The probes not only exhibited higher photothermal conversion efficiency (42.07%) and stronger photoacoustic signal than those of gold nanoparticle controls, but also possessed dual-responsive doxorubicin release upon pH and photothermal stimulation.…”

Section: Biomedical Applications Of Pda Coatingsmentioning

confidence: 99%

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

et al. 2020

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Biological structures have emerged through millennia of evolution, and nature has fine-tuned the material properties in order to optimise the structure-function relationship. Following this paradigm, polydopamine (PDA), which was found to be crucial for the adhesion of mussels to wet surfaces, was hence initially introduced as a coating substance to increase the chemical reactivity and surface adhesion properties. Structurally, polydopamine is very similar to melanin, which is a pigment of human skin responsible for the protection of underlying skin layers by efficiently absorbing light with potentially harmful wavelengths. Recent findings have shown the subsequent release of the energy (in the form of heat) upon light excitation, presenting it as an ideal candidate for photothermal applications. Thus, polydopamine can both be used to (i) coat nanoparticle surfaces and to (ii) form capsules and ultra-small (nano)particles/nanocomposites while retaining bulk characteristics (i.e., biocompatibility, stability under UV irradiation, heat conversion, and activity during photoacoustic imaging). Due to the aforementioned properties, polydopamine-based materials have since been tested in adhesive and in energy-related as well as in a range of medical applications such as for tumour ablation, imaging, and drug delivery. In this review, we focus upon how different forms of the material can be synthesised and the use of polydopamine in biological and biomedical applications. platform is highlighted ( Figure 1A). Then, theoretical and experimental proof of the chemical formation of polydopamine-based structures is summarised ( Figure 1B,C). This is then followed by descriptions of the unique (physicochemical) properties of polydopamine. Their applications as adhesive and in energy-related applications are also highlighted ( Figure 1D). Throughout, their wide range of applications in the biomedical field (thanks to their biocompatibility) is thoroughly explained. This includes examples of theranostic and drug delivery applications derived from different types of polydopamine-based configurations: adhesive, particle coating agent, capsule, and NPs/composites, respectively ( Figure 1C,E). Lastly, some challenges to make PDA into functional tools for future clinical applications are envisaged. Materials 2019, 12, x FOR PEER REVIEW 2 of 22polydopamine-based structures is summarised ( Figure 1B,C). This is then followed by descriptions of the unique (physicochemical) properties of polydopamine. Their applications as adhesive and in energy-related applications are also highlighted ( Figure 1D). Throughout, their wide range of applications in the biomedical field (thanks to their biocompatibility) is thoroughly explained. This includes examples of theranostic and drug delivery applications derived from different types of polydopamine-based configurations: adhesive, particle coating agent, capsule, and NPs/composites, respectively ( Figure 1C,E). Lastly, some challenges to make PDA into functional tools for future clinical applicatio...

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Section: Biomedical Applications Of Pda Coatingsmentioning

confidence: 99%

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

et al. 2020

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“…In addition to the compensating effect of multiple therapeutic methods, the combination of merits of single therapy also exhibits considerable therapeutic effect [120,121]. For example, Nokyoung et al assembled AuNPs on DNA hydrogels for effective chemo/PTT [122].…”

Section: Chemotherapy/phototherapymentioning

confidence: 99%

DNA Nanotechnology for Multimodal Synergistic Theranostics

Qiao

Song

et al. 2021

J. Anal. Test.

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Over the past decade, DNA nanotechnology has developed rapidly due to its unique characteristics, such as excellent biocompatibility, high programmability, good predictability, automatically chemical synthesis, and so on. So far, a variety of DNA-based nanostructures, from small to large and simple to complex, have been designed and synthesized with controllable size and shape in one, two, or three dimensions. Therefore, DNA has become a kind of competitive materials for biosensing, bioimaging and biomedicine. In particular, the integration of DNA nanotechnology with multimodal synergistic theranostics can not only achieve accurate cancer diagnosis by the sensitive and accurate detection of cancer biomarkers, but also achieve enhanced anti-cancer therapeutic efficacy, which promote the development of DNA nanotechnology and nanomedicine. In this review, we first give a comprehensive introduction of DNA nanotechnology, and then summarize the DNA self-assembly and amplification strategies for the construction of functional nanoplatforms for multimodal synergistic theranostics. Finally, the challenges and opportunities faced by DNA nanotechnology in biomedicine are discussed.

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“…The pH-dependent nanoparticles, quenched by PDA, could be photoactivated only in the acidic environment of a tumor whereby they released the photosensitizer and displayed multimodal imaging capability due to strong affinity between metal ions and PDA and exhibit high antitumor PDT efficacy ( Dong et al, 2018 ). Various metal ions have been loaded onto PDA nanoparticles for bioimaging and photothermal cancer therapy simultaneously ( Miao et al, 2015 ; Ge et al, 2017 ; Feng et al, 2020 ; Liu et al, 2020 ). Photocatalytic organic nanoparticles composed of flavin-conjugated PDA NPs have been described to display xenobiotic-degrading enzyme analogous activity ( Fruk and Crocker, 2019 ).…”

Section: Broad Spectrum Of Polydopamine Nanoparticles As Biomaterialsmentioning

confidence: 99%

Recent Advances in a Polydopamine-Mediated Antimicrobial Adhesion System

et al. 2021

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The drug resistance developed by bacteria during antibiotic treatment has been a call to action for researchers and scientists across the globe, as bacteria and fungi develop ever increasing resistance to current drugs. Innovative antimicrobial/antibacterial materials and coatings to combat such infections have become a priority, as many infections are caused by indwelling implants (e.g., catheters) as well as improving postsurgical function and outcomes. Pathogenic microorganisms that can exist either in planktonic form or as biofilms in water-carrying pipelines are one of the sources responsible for causing water-borne infections. To combat this, researchers have developed nanotextured surfaces with bactericidal properties mirroring the topographical features of some natural antibacterial materials. Protein-based adhesives, secreted by marine mussels, contain a catecholic amino acid, 3,4-dihydroxyphenylalanine (DOPA), which, in the presence of lysine amino acid, empowers with the ability to anchor them to various surfaces in both wet and saline habitats. Inspired by these features, a novel coating material derived from a catechol derivative, dopamine, known as polydopamine (PDA), has been designed and developed with the ability to adhere to almost all kinds of substrates. Looking at the immense potential of PDA, this review article offers an overview of the recent growth in the field of PDA and its derivatives, especially focusing the promising applications as antibacterial nanocoatings and discussing various antimicrobial mechanisms including reactive oxygen species-mediated antimicrobial properties.

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Amplified Photoacoustic Signal and Enhanced Photothermal Conversion of Polydopamine-Coated Gold Nanobipyramids for Phototheranostics and Synergistic Chemotherapy

Cited by 73 publications

References 57 publications

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

From Bioinspired Glue to Medicine: Polydopamine as a Biomedical Material

DNA Nanotechnology for Multimodal Synergistic Theranostics

Recent Advances in a Polydopamine-Mediated Antimicrobial Adhesion System

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