Amyloid Deposition of the Breast

Gluck, Brad S.; Cabrera, Julio; Strauss, B; Ricca, Richard; Brancaccio, W; Tamsen, Ali

doi:10.2214/ajr.175.6.1751590

Cited by 22 publications

(15 citation statements)

References 5 publications

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“…The remaining four reports were in localized forms. In the previous reports, the shapes of the microcalcifications varied according to clustered (4, 5), pleomorphic (4, 5), fine linear and branching (1, 2), and smooth branching rod-like (2, 3) shapes. All the previous mammographic findings were assessed either as intermediate or suspicious of malignancy, and pathological confirmations were recommended (1-5).…”

Section: Discussionmentioning

confidence: 95%

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Primary Breast Amyloidosis Presenting as Microcalcifications Only

et al. 2013

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Amyloidosis is a rare disease characterized by the formation of pathological protein deposits in organs or tissues. It is typically a systemic disease which can occur in a localized form. Amyloidosis of the breast is uncommon. Common mammographic findings of breast amyloidosis are multiple nodules with or without calcifications. We report a case of primary localized breast amyloidosis presenting suspicious microcalcifications on mammography without associated masses. Mammography in a 72-year-old woman displayed multiple, linearly distributed, irregular and rod-like calcifications in the subareolar area of the left breast. The patient underwent surgical excision under mammo-guided needle localization and the pathology was confirmed to be breast amyloidosis.

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Section: Discussionmentioning

confidence: 95%

“…Only five cases that were presented solely as microcalcifications have been reported (1-5). One case was breast involvements of systemic amyloidosis within a patient with a 15-year history of multiple myeloma (3). The remaining four reports were in localized forms.…”

Section: Discussionmentioning

confidence: 99%

Primary Breast Amyloidosis Presenting as Microcalcifications Only

et al. 2013

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“…The proteins can be found as a conglomerate, in the masslike or tumoral form, or diffusely throughout the breast (4). Amyloid deposition in the breast can present clinically as a palpable mass or as a non-palpable abnormality on mammography (6). Amyloidosis has also presented clinically as diffuse breast heaviness, engorgement and skin thickening, mimicking inflammatory carcinoma (7).…”

Section: Discussionmentioning

confidence: 99%

“…Rather, amyloid deposition in the breast is often described as mimicking breast carcinoma and warranting biopsy. Mammographically, amyloidosis in the breast has presented as a suspicious mass with or without microcalcifications, as well as microcalcifications alone (6,(8)(9)(10). In a case series of 7 patients with localized amyloidosis of the breast, all patients presented with calcifications on screening mammography (9).…”

Section: Discussionmentioning

confidence: 99%

“…In a case series of 7 patients with localized amyloidosis of the breast, all patients presented with calcifications on screening mammography (9). Calcifications associated with amyloid deposition in the breast have been described as smooth branching rodlike, elongated, curvilinear, and radiolucent centered, with distribution patterns of grouped, segmental and even scattered (4,6).…”

Section: Discussionmentioning

confidence: 99%

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Localized Amyloidosis of the Breast Mimicking Breast Cancer: Radiologic-Pathologic Correlation

Coletti¹,

Joe²,

Jeffries³

et al. 2015

MRAJ

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Abstract:Amyloidosis localized to the breast is uncommon. It may present with nonspecific imaging characteristics including a suspicious mass with or without calcifications, calcifications alone, or even with features mimicking inflammatory carcinoma of the breast. Amyloidosis has also been described coexistent with primary carcinoma of the breast, further confounding the imaging spectrum. We describe a case of amyloidosis localized to the breast presenting as a new mass with imaging features highly suggestive of malignancy.

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