An 11-Year-Old Girl With Rare Diagnosis of Meier-Gorlin Syndrome Accompanied by Neonatal Seizure, Mental Retardation, and Attention Deficit Hyperactivity Disorder: A Case Report and Review of Literature

Koomanaee, Shahin; Dalili, Setila; Nouri, Seyyedeh Azade Hoseini; Jalali, Seyedeh Zohreh; Tabrizi, Manijeh; Aldaghi, Ghazaleh; Rad, Afagh Hassanzadeh

doi:10.18502/acta.v60i9.11102

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“…Various factors may be associated with childhood obesity including nutrition in early life, excessive gestational weight gain,[ 2 ] maternal smoking during pregnancy, parent feeding practices, duration of breastfeeding, body mass index (BMI), father's weight, birth order, age, birth weight, and rapid weight gain (RWG). [ 3 4 ]…”

Section: Introductionmentioning

confidence: 99%

Predicting childhood overweight status by accelerated weight gain from neonatal period to infancy

Dalili

Koohmanaee

Badeli

et al. 2023

Journal of Research in Medical Sciences

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Background: The increased prevalence of obesity in early childhood is a public health problem. Childhood obesity may affect cardiorespiratory fitness and can induce obesity and its comorbidities in adulthood. We aimed to assess childhood overweight status by accelerated weight gain during infancy. Materials and Methods: This is a historical cohort that was conducted on 637 7-year-old students of Guilan province, north of Iran. Data were collected, including demographic characteristics, weight at 4, 6, 12, and 18 months, and clinical examination. The ROC curve was designated based on the standardized z-scores, and the most appropriate cutoff point by sensitivity and specificity was noted for predicting obesity at 7 years. Rapid weight gain (RWG) was also assessed. Results: Among participants, 334 (53.3%) were female. In this study, the mean and standard deviation of RWG in 0–4 months, 0–6 months, 0–12 months, and 0–18 months were 3.50 ± 0.89, 4.64 ± 1.02, 6.54 ± 1.21, and 8.00 ± 1.46 kg, respectively. The highest AUC was dedicated to 0–18 months (0.7 ± 0.05) and the suitable cut-off for RWG in this interval was 8.55 kg with 65.5% and 72.0% sensitivity and specificity, respectively. Conclusion: Although in the previous investigations, the changes in the first 3 years of life had a significant role in further complications, regarding our results, it seems that even earlier consideration of excess weight gain may be necessary.

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Section: Introductionmentioning

confidence: 99%