An active ingredient of Cat's Claw water extracts

Quinic acid is a biologically active component of the Uncaria tomentosa extract C-Med 100®

“…(iii) When the bioactive fraction was neutralized by acidifying with 1N HCl, only QA acid could be structurally elucidated (Ref. [16] and Sheng et al [17] An active ingredient of Cat's Claw water extracts. Identification and efficacy of quinic acid, submitted for publication).…”

“…QA was isolated from C-Med 100R, as already described in detail elsewhere (Ref. [16] and Sheng et al [17] An active ingredient of Cat's Claw water extracts. Identification and efficacy of quinic acid, submitted for publication).…”

“…The eluted material from one fraction was found to inhibit proliferation of HL-60 cells similarly to the CMed 100R extract itself. A component in this biologically active fraction was identified by MALDI mass spectrometry as quinic acid (QA), as described in detail elsewhere (Sheng et al [17] An active ingredient of Cat's Claw water extracts. Identification and efficacy of quinic acid, submitted for publication).…”

“…These are primarily involved in the anti-inflammatory effects associated with the efficacious properties of these extracts (Ref. [16] and Sheng et al [17] Active ingredient of Cat's Claw water extracts. Identification and efficacy of quinic acid, submitted for publication).…”

Uncaria tomentosa and Uncaria guianensis an agronomic history to be written

“…They are divided into indole tetracyclic alkaloids (corynanthein, dihydrocorynanthein, hirsuthein, and hirsutine) oxindole alkaloids (rhynchophylline, isorhynchophylline, corynoxein, isocorynoxein, rotundifolin, and isorotundifolin) indole pentacyclic alkaloids (akuamigine, augustine, augustolin, isoamalicin, and tetrahydroalstonin) and oxindole alkaloids (speciophylline, mitraphylline, isomitraphylline, pteropodin, isopteropodin, and uncarin F), and glycoindole alkaloids (3α-dihydrocadambine and dolichantosin) (LAUS et al, 1997;FALKIEWICZ & LUKASIAK, 2001;LUNA-PALENCIA et al, 2013). Besides the alkaloids, the triterpenic heterosides (derived from the quinovic acid) and polyphenols (especially tannin) are also highlighted (PAVEI et al, 2012;SHENG et al, 2005).…”