An Adjustable-Length Intramedullary Nail: Development and Mechanical Evaluation in Cervine Tibiae

Throop, Alexander D. W.; Clark, Alexander Martin; Kuxhaus, Laurel

doi:10.1115/1.4030152

Cited by 2 publications

(1 citation statement)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In order to solve the negative effects of conventional metal INs in long bone fracture repair, the researchers studied the variety of degradable biomaterials in recent years [27][28][29]. However, the demands for unique slender structure of the INs and extremely high mechanical strength are difficult to meet [30][31][32]. Furthermore, the manufacturing technique of biodegradable IN still needs to be improved, and a good universal manufacturing technique for fabricating high-strength biodegradable IN is needed as well.…”

Section: Introductionmentioning

confidence: 99%

Magnesium-Containing Silicate Bioceramic Degradable Intramedullary Nail for Bone Fractures

Shao

Jing

et al. 2022

Crystals

View full text Add to dashboard Cite

Intramedullary nails (INs) have significant advantages in rigid fracture fixation. Due to the stress shielding effect and lack of biological activity, traditional metal INs often lead to delay union or nonunion fracture healing. Undegradable metals also need to be removed by a second surgery, which will impose a potential risk to the patient. Current degradable biomaterials with low strength cannot be used in INs. Manufacturing high-strength biodegradable INs (BINs) is still a challenge. Here, we reported a novel high strength bioactive magnesium-containing silicate (CSi-Mg) BIN. This BIN is manufactured by using casting, freeze drying, and sintering techniques and has extremely high bending strength and stable internal and external structures. The manufacturing parameters were systematically studied, such as the paste component, freeze-drying process, and sintering process. This manufacturing method can be applied to various sizes of BINs. The CSi-Mg BIN also has good bioactivity and biodegradation properties. This novel bioactive BIN is expected to replace the traditional metal INs and become a more effective way of treating fractures.

show abstract

Section: Introductionmentioning

confidence: 99%

Magnesium-Containing Silicate Bioceramic Degradable Intramedullary Nail for Bone Fractures

Shao

Jing

et al. 2022

Crystals

View full text Add to dashboard Cite

show abstract

A Proximally-Adjustable Variable Length Intramedullary Nail: Ex Vivo Quasi-Static and Cyclic Loading Evaluation

Hedgeland

Clark²,

Ciani

et al. 2017

Journal of Medical Devices

View full text Add to dashboard Cite

An adjustable-length intramedullary (IM) nail may reduce both complications secondary to fracture fixation and manufacturing costs. We hypothesized that our novel nail would have suitable mechanical performance. To test this hypothesis, we manufactured three prototypes and evaluated them in quasi-static axial compression and torsion and quasi-static four-point bending. Prototypes were dynamically evaluated in both cyclic axial loading and four-point bending and torsion-to-failure. The prototypes exceeded expectations; they were comparable in both quasi-static axial stiffness (1.41 ± 0.37 N/m in cervine tibiae and 2.30 ± 0.63 in cadaver tibiae) and torsional stiffness (1.05 ± 0.26 N·m/deg in cervine tibiae) to currently used nails. The quasi-static four-point bending stiffness was 80.11 ± 09.360, greater than reported for currently used nails. A length-variance analysis indicates that moderate changes in length do not unacceptably alter bone-implant axial stiffness. After 103,000 cycles of axial loading, the prototype failed at the locking screws, comparable to locking screw failures seen clinically. The prototypes survived 1,000,000 cycles of four-point bend cyclic loading, as indicated by a consistent phase angle throughout cyclic loading. The torsion-to-failure test suggests that the prototype has adequate resistance to applied torques that might occur during the healing process. Together, these results suggest that our novel IM nail performs sufficiently well to merit further development. If brought to market, this adjustable-length IM nail could reduce both patient complications and healthcare costs.

show abstract

An Adjustable-Length Intramedullary Nail: Development and Mechanical Evaluation in Cervine Tibiae

Cited by 2 publications

References 18 publications

Magnesium-Containing Silicate Bioceramic Degradable Intramedullary Nail for Bone Fractures

Magnesium-Containing Silicate Bioceramic Degradable Intramedullary Nail for Bone Fractures

A Proximally-Adjustable Variable Length Intramedullary Nail: Ex Vivo Quasi-Static and Cyclic Loading Evaluation

Contact Info

Product

Resources

About