An adult case of celiac sprue triggered after an ileal resection for perforated Meckel’s diverticulum

Topal, Firdevs

doi:10.3748/wjg.15.4075

Cited by 4 publications

(4 citation statements)

References 13 publications

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“…A search in the literature revealed 24 cases of CeD that were discovered after upper GI surgery, of which ten occurred after pancreaticoduodenectomy (Table 2). [9][10][11][12][13][14][15][16] Remarkably, all those cases presented with marked weight loss, just as in our patient. Ours is the oldest patient described in the literature to develop CeD after upper GI surgery.…”

supporting

confidence: 61%

“…8 Several reports have suggested that various surgical interventions, particularly upper gastrointestinal (GI) operations such as gastrectomy, Nissen fundoplication and Roux-en-Y gastric bypasses, may unmask undiagnosed CeD. [9][10][11][12][13][14][15][16] In this report we described a patient diagnosed with CeD following a pylorus-preserving pancreaticoduodenectomy (PPPD). Before surgery there was no clue as to the presence of CeD.…”

mentioning

confidence: 99%

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Celiac disease newly diagnosed after pancreaticoduodenectomy: A case report and review of the literature

Al-Toma

Meeberg

Al–Toma

2021

J of Digest Diseases

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supporting

confidence: 61%

mentioning

confidence: 99%

Celiac disease newly diagnosed after pancreaticoduodenectomy: A case report and review of the literature

Al-Toma

Meeberg

Al–Toma

2021

J of Digest Diseases

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“…16,17 Subsequently, however, unmasking has been described after a wide variety of procedures, both intra-abdominal and extra-abdominal. 9,10,[18][19][20][21] A more likely explanation is perioperative stress, which leads to activation of celiac disease.…”

Section: Discussionmentioning

confidence: 99%

Surgical Aspects of Celiac Disease

Thompson

Meyer

2015

The American Surgeon™

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Celiac disease, characterized by intestinal inflammation and malabsorption, occurs in 1 per cent of the population and is often undiagnosed. These patients are at increased risk for surgical procedures resulting from symptoms, associated intestinal disorders, and malignancy. Our aim was to determine the incidence and outcome of abdominal operations in patients with celiac disease. Records of 512 adult patients with celiac disease evaluated over a 22-year period were reviewed. Operations were classified as related or unrelated to celiac disease. One hundred eighty-eight (36%) of 512 patients underwent abdominal operations. One hundred twenty-seven (68%) of the 188 patients had unrelated procedures. Sixty-one (32%) had operations considered related to celiac disease. Twenty-six (43%) of 61 with related procedures were diagnosed preoperatively. Procedures were performed for pain, obstruction, motility disorders, and malignancy. Six patients had recurrent pancreatitis. Seven patients underwent liver transplantation. Thirty-five (57%) related procedures led to the diagnosis of celiac disease including “unmasking” (n = 25) and diagnostic findings (n = 10). One-third of patients with celiac disease undergo abdominal operations of which one-third are related to celiac disease. Operations are related to complications of celiac disease and often lead to the initial diagnosis.

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“…Subsequent evaluation then leads to the diagnosis, termed "unmasking" [6]. Initial reports of this phenomenon occurred following upper gastrointestinal procedures such as fundoplication and gastrectomy [6]; however, unmasking has been subsequently described following a variety of intraabdominal and extraabdominal procedures [7][8][9][10][11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Bariatric Procedures Unmasking Celiac Disease

2014

J Obes Bariatr Surg

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Celiac disease is being recognized more frequently but often remains undiagnosed. Celiac disease patients are increasingly obese. Major operation in patients with celiac disease may cause symptoms which lead to the diagnosis, termed "unmasking." We report three patients undergoing bariatric procedures which led to unmasking.Three patients undergoing bariatric procedures for morbid obesity were subsequently diagnosed with celiac disease. A 42-yearold female underwent gastric bypass. Her body mass index was 77 preoperatively and open gastric bypass with a 150 cm Roux Limb was performed. At 18 months her body mass index was 51 and she had no diarrhea. A malabsorptive revision moved the Roux Limb connection to 60 cm proximal to the cecum. One year later she had a body mass index of 36 and diarrhea. Persistent diarrhea and weight loss in the following two years led to serologic diagnosis of celiac disease. On a gluten-free diether diarrhea improved and her weight increased 6 kg. A 30-year-old female underwent gastric band. Her body mass index was 46 preoperatively. After multiple adjustments a band slip repair was performed at two years and the band was removed at four years. Body mass index was 42 at that time. Within a few months she developed early satiety, abdominal pain and distension, and hepatomegaly. Serology and histology diagnosed celiac disease and a gluten-free diet was instituted. A 36-year-old female underwent biliopancreatic diversion. Her body mass index was 48 preoperatively and decreased to 22 in two years. Persistent diarrhea led to serologic evaluation for celiac disease. She was started on a gluten-free diet and her body mass index increased to 27 at five years and 30 at ten years postoperatively.Celiac disease should be suspected and evaluated in patients who develop suggestive symptoms after bariatric procedures, including those associated with malabsorption.

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An adult case of celiac sprue triggered after an ileal resection for perforated Meckel’s diverticulum

Cited by 4 publications

References 13 publications

Celiac disease newly diagnosed after pancreaticoduodenectomy: A case report and review of the literature

Celiac disease newly diagnosed after pancreaticoduodenectomy: A case report and review of the literature

Surgical Aspects of Celiac Disease

Bariatric Procedures Unmasking Celiac Disease

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