The odd symplectic Grassmannian IG :" IGpk, 2n`1q parametrizes k dimensional subspaces of C 2n`1 which are isotropic with respect to a general (necessarily degenerate) symplectic form. The odd symplectic group acts on IG with two orbits, and IG is itself a smooth Schubert variety in the submaximal isotropic Grassmannian IGpk, 2n`2q. We use the technique of curve neighborhoods to prove a Chevalley formula in the equivariant quantum cohomology of IG, i.e. a formula to multiply a Schubert class by the Schubert divisor class. This generalizes a formula of Pech in the case k " 2, and it gives an algorithm to calculate any multiplication in the equivariant quantum cohomology ring.