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Background: COVID-19 has tormented the global health and economy like no other event in the recent past. Researchers and policymakers have been working strenuously to end the pandemic completely. Methodology/ Principal Findings: Infectious disease dynamics could be well-explained at an individual level with established contact networks and disease models that represent the behaviour of the infection. Hence, an Agent-Based Model, SHIVIR (Susceptible, Infected, Admitted, ICU, Ventilator, Recovered, Immune) that can assess the transmission dynamics of COVID-19 and the effects of Non-Pharmaceutical Interventions (NPI) was developed. Two models were developed using to test the synthetic populations of Rangareddy, a district in Telangana state, and the state itself respectively. NPI such as lockdowns, masks, and social distancing along with the effect of post-recovery immunity were tested across scenarios. The actual and forecast curves were plotted till the unlock phase began in India. The Mean Absolute Percentage Error of scenario MD100I180 was 6.41 percent while those of 3 other scenarios were around 10 percent each. Since the model anticipated lifting of lockdowns that would increase the contact rate proportionately, the forecasts exceeded the actual estimates. Some possible reasons for the difference are discussed. Conclusions: Models like SHIVIR that employ a bottom-up Agent-Based Modelling are more suitable to investigate various aspects of infectious diseases owing to their ability to hold details of each individual in the population. Also, the scalability and reproducibility of the model allow modifications to variables, disease model, agent attributes, etc. to provide localized estimates across different places.
Background: COVID-19 has tormented the global health and economy like no other event in the recent past. Researchers and policymakers have been working strenuously to end the pandemic completely. Methodology/ Principal Findings: Infectious disease dynamics could be well-explained at an individual level with established contact networks and disease models that represent the behaviour of the infection. Hence, an Agent-Based Model, SHIVIR (Susceptible, Infected, Admitted, ICU, Ventilator, Recovered, Immune) that can assess the transmission dynamics of COVID-19 and the effects of Non-Pharmaceutical Interventions (NPI) was developed. Two models were developed using to test the synthetic populations of Rangareddy, a district in Telangana state, and the state itself respectively. NPI such as lockdowns, masks, and social distancing along with the effect of post-recovery immunity were tested across scenarios. The actual and forecast curves were plotted till the unlock phase began in India. The Mean Absolute Percentage Error of scenario MD100I180 was 6.41 percent while those of 3 other scenarios were around 10 percent each. Since the model anticipated lifting of lockdowns that would increase the contact rate proportionately, the forecasts exceeded the actual estimates. Some possible reasons for the difference are discussed. Conclusions: Models like SHIVIR that employ a bottom-up Agent-Based Modelling are more suitable to investigate various aspects of infectious diseases owing to their ability to hold details of each individual in the population. Also, the scalability and reproducibility of the model allow modifications to variables, disease model, agent attributes, etc. to provide localized estimates across different places.
PurposeThe textile industry contributes 2 and 3% to the global and Indian Gross Domestic Product (GDP), respectively. India supplies a quarter of global cotton yarn. Yet, most yarn manufacturing companies use outdated methods and lack organisational skills and strategies. Improvement in processes in India could significantly help the industry worldwide.Design/methodology/approachThe variables that influence the performance of the system were identified. Their interrelationships and impact were identified from the employees in the chosen case study, a yarn manufacturing industry. A System Dynamics (SD) approach was employed to study the benefits of implementing 5S lean strategies. The impact of each variable on various performance measures such as throughput, Work In Progress, processing time, waiting time, idle time, over-processing and scraps was analysed.FindingsImprovement in outcomes reflected an enhanced adoption of leanness in the industry. The decision-makers can utilise this study to optimise the necessary parameters in the system and attain the desired productivity levels. Better resource management and reduced processing time helped increase the despatch rate by 9.735% and decrease the WIP by 23.01%. Time management helped to reduce the inventory, idle time and waiting time. Over-processing, defects and scraps were minimised, indicating a shift towards lean.Research limitations/implicationsThis study pioneers the use of SD simulation models for optimising yarn manufacturing using lean strategies. Improvement in performance measures by integrating these strategies opens avenues for future research using multiple approaches to address a problem.Practical implicationsImplementing 5S lean principles and simulations enhances productivity, reduces waste and optimises resource management for the yarn manufacturing industry. Decision-makers can employ simulation to witness the outcomes of their changes without investing cost and time and without associated implementation risks.Originality/valueThe use of a simulation model to witness the benefits of incorporating lean strategies in yarn production has not been explored. This approach could help the managers and policymakers understand their existing system's shortcomings and critical areas that require improvement.
Background: More than 278 million cases and more than 5.4 million deaths due to coronavirus disease (COVID-19) were reported worldwide by the end of 2021. More than 34 million cases and more than 478,000 deaths have been reported in India. Epidemiologists, physicians and virologists are working on a number of conceptual, theoretical or mathematical modelling techniques in the battle against COVID-19. Protocol: This systematic review aims to provide a comprehensive review of published mathematical models on COVID-19 in India and the concepts behind the development of mathematical models on COVID-19, including assumptions, modelling techniques, and data inputs. Initially, related keywords and their synonyms will be searched in the Global Literature on Coronavirus Disease database managed by World Health Organisation (WHO). The database includes searches of bibliographic databases (MEDLINE, Scopus, Web of Science, EMBASE etc.,), preprints (MEDRXIV), manual searching, and the addition of other expert-referred scientific articles. This database is updated daily (Monday through Friday). Two independent reviewers will be involved in screening the titles and abstracts at the first stage and full-texts at the second stage, and they will select studies as per the inclusion and exclusion criteria. The studies will be selected for their quality, transparency, and ethical aspects, using the Overview, Design concepts, Details (ODD) protocol and International Society for Pharmacoeconomics and Outcomes Research-Society for Medical Decision Making (ISPOR-SMDM) guidelines. Data will be extracted using standardized data extraction tools and will be synthesized for analysis. Disagreements will be resolved through discussion, or with a third reviewer. Conclusions: This systematic review will be performed to critically examine relevant literature of existing mathematical models of COVID-19 in India. The findings will help to understand the concepts behind the development of mathematical models on COVID-19 conducted in India in terms of their assumptions, modelling techniques, and data inputs.
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