Abstract. It has long been established that adverse drivers' behaviors, including behavior relating to distracted driving, propensities for risk-taking, and disregard for tra c rules, have been critical determinants with regard to the likelihood of a vehicle crash and its resulting injury severity. Socio-economic/educational/cultural factors have signi cant positive e ects on tra c-related fatalities. Using crash data from Iran over a six-year period from January 1, 2006 to December 31, 2011, this paper estimates a mixed logit model to investigate the unsafe driving behavior e ects on driver-injury severities in a vehicle collision on interprovincial routes. The methodological approach allows the parameters to vary across observations as opposed to a xed parameter model. The results showed random e ects of female drivers, separated bi-directional route and clear weather condition for no injury severity function, following too closely for minor injury function, and average annual daily tra c for severe injury function. Several factors were found to signi cantly increase the likelihood of severe injury crashes including disregarding tra c rules, exceeding the speed limit, improper overtaking/passing, and driving in an erratic and negligent manner. The results of this paper will further help decision-makers to better understand the contributing factors on crash injury severity and implement treatments to reduce the crash severity and improve transportation safety.