An aggregation-induced emission (AIE) active probe for multiple targets: a fluorescent sensor for Zn²⁺and Al³⁺& a colorimetric sensor for Cu²⁺and F⁻

Abstract

A rationally designed probe L, which consists of both cation and anion binding sites, is capable of displaying interesting aggregation induced emission (AIE) properties. L not only can sense Al(3+) and Zn(2+) through selective turn-on fluorescence responses in 9 : 1 methanol-HEPES buffer (5 mM, pH 7.3; 9 : 1, v/v) medium due to metal ion triggered AIE activity, but also can distinguish them through individual emission signals. L can also detect Cu(2+) in mixed buffer medium and F(-) in acetonitrile through sharp colorimetric responses. All the sensing processes are conspicuous through the naked eye. A theoretical study strongly backed the proposed sensing mechanisms.

A single fluorescent chemosensor for multiple targets of Cu2+, Fe2+/3+ and Al3+ in living cells and a near-perfect aqueous solution

“…S4 †), which was within the range of those (10 3 to 10 12 ) previously reported for chemosensors toward Cu 2+ . [56][57][58][59][60][61] As shown in Fig. S5, † the detection limit (3s/k) 62 of 1 for Cu 2+ was determined to be 1.25 mM which was much lower than that (31.5 mM) recommended by WHO in drinking water.…”

Dual recognition of Al3+ and Zn2+ ions by a novel probe based on diarylethene and its application

“…The EDTA disodium salt solution was also dissolved in deionized water. NMR spectra were obtained with a Bruker AV400 (400 MHz) spectrometer using DMSO-d 6 as the solvent and tetramethylsilane as the internal standard. UV/Vis absorption spectra were measured on an Agilent 8453 UV/Vis spectrophotometer.…”

“…1 Among many metals, aluminum is the most abundant metallic element in the Earth's crust, 2,3 and its compounds are widely used in dye production, and the paper and food industries. [4][5][6] Aluminum is not a necessary element for the functioning of the human body, and it may accumulate in the organs and tissues for a long time before it is excreted, so the excessive and deciency of aluminum will result negative effects on the human body. [7][8][9][10] For instance, aluminum is linked to Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, colic, rickets, gastrointestinal problems, interference with the metabolism of calcium, and memory loss.…”

“…Zinc is one of the transition metals in the human body found in quantities second only to iron, and due to its biological signicance, a large body of research exists for zinc. [6][7][8][9][10][11][12][13][14][15][16][17][18] It is well known that zinc exists in various enzymes and has multiple functions in basic biological processes, such as apoptosis, gene transcription, immune function, pathology, muscle contraction, neural signal transmission, and immune function. [19][20][21] Therefore, the correct amount of zinc in the body is also important.…”

Fluorescent detection of multiple ions by two related chemosensors: structural elucidations and logic gate applications

“…5 Notably, inputs and outputs critically depend on the functional groups being offered by a probe and/or a chemosensor. 6 It is well known that both cations and anions are required in various biological processes while both their excess as well as deciency may have detrimental effects. 7 For example, essential Cu 2+ ion can cause serious complications due to its excess.…”