An AIE fluorescent sensor for rapid and selective detection of phosgene

Abstract

Herein, an aggregation-induced emission (AIE)-based sensor, 4-(1,2,2-Triphenylvinyl)benzoxime (TPE-phos), has been rationally designed for phosgene detection. The sensor has a tetraphenylethylene unit combined with an oxime moiety. TPE-phos undergoes nitrile formation...

A salicylaldoximate-based AIE probe for the detection of the nerve agent simulant DCP

“…But in our previous work, a TPE-based probe we had designed with the same oxime group as TPE-D could detect phosgene via AIE fluorescence due to the transformation of the oxime to a nitrile group. 26 In this work, the oxime group in the salicylaldoximate moiety of TPE-D could also convert to a nitrile group in the presence of phosgene, forming a compound with an orthohydroxy arylnitrile structure (namely TPE-OH). The compound was further confirmed by mass spectral analysis (Fig.…”

“…In our previous work, we realized the importance of a discrepancy in aggregative propensity between an AIE probe and its generated product during the detection of a target analyte. 26 In this work, an AIE probe TPE-D, consisting of a TPE unit and a salicylaldoximate functional moiety, was designed for the detection of DCP. We anticipated that the TPE-D probe could react with DCP on the site of salicylaldoximate, thus producing (a) molecule(s) with structure(s) different from TPE-D.…”

“…17,[19][20][21][22][23][24][25] Previously, we designed an AIE probe (TPE-phos) for phosgene detection, which has a tetraphenylethylene unit (TPE) combined with an oxime moiety. 26 TPE-phos undergoes the formation of nitrile after the oxime moiety reacts with phosgene, which within seconds shows a significant ''light-up'' fluorescence change due to the AIE effect. Also, TPE-phos can react with diethyl chlorophosphate (DCP), an OP nerve agent simulant, to generate the oxime's OP ester.…”

Recent advances in aggregation-induced emission (AIE)-based chemosensors for the detection of organic small molecules

“…Similarly, Wu et al synthesized another fluorescent probe ( D70 ) with a TPE unit and oxime moiety. 411 D70 shows a fluorescent enhancement upon exposure to phosgene, with a calculated LOD of 9.3 nM.…”

Polysaccharide restriction on bipyridyl isomers for multicolor emissions

“…Luminophores that can emit light under ultraviolet light have been widely used in the fields of display, 1 bioimaging, 2 chemosensing, 3,4 etc. These materials for various biomedical applications are divided into inorganic nanomaterials (quantum dots 5 and carbon dots 6 ), nonconjugated chromophores, 7 and conventional organic dyes.…”