2004
DOI: 10.1007/s00125-004-1599-9
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An alarmingly high prevalence of diabetic nephropathy in Asian type 2 diabetic patients: the MicroAlbuminuria Prevalence (MAP) Study

Abstract: Aim/hypothesis: Microalbuminuria represents the earliest clinical evidence of diabetic nephropathy and is a marker of increased cardiovascular morbidity and mortality. Its early detection allows the implementation of individualised and aggressive intervention programmes to reduce cardiovascular risk factors. There is limited information on the prevalence of microalbuminuria among hypertensive type 2 diabetic patients in Asia. Methods: This cross-sectional epidemiological study aimed to assess the prevalence of… Show more

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Cited by 214 publications
(184 citation statements)
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“…In a recent meta-analysis, Asians were found to have a lower risk of developing cardiovascular disease but a higher risk of renal disease than Caucasians [22,23]. In the present analysis, patients with chronic HBV infection were younger, had earlier onset of disease and were more likely to be insulin-treated and have retinopathy at baseline.…”
Section: Discussionmentioning
confidence: 47%
“…In a recent meta-analysis, Asians were found to have a lower risk of developing cardiovascular disease but a higher risk of renal disease than Caucasians [22,23]. In the present analysis, patients with chronic HBV infection were younger, had earlier onset of disease and were more likely to be insulin-treated and have retinopathy at baseline.…”
Section: Discussionmentioning
confidence: 47%
“…Thus, the prevalence of microalbuminuria may be over-estimated if a random morning urine sample is used. In their paper, Wu et al [1] do not state the proportion of urine samples that were random morning samples, but I speculate that it could have been the majority given the cross-sectional nature of the study. It is my opinion that, in view of the abovementioned limitations, the high prevalence of microalbu-…”
mentioning
confidence: 98%
“…
To the Editor: Wu et al [1] studied the prevalence of albuminuria in 5,549 Asian type 2 diabetic patients. The reported prevalence of microalbuminuria in this group, 39.8%, is remarkably high; higher than the prevalence reported in other populations [2].
…”
mentioning
confidence: 99%
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“…APCSC also showed an association between diabetes and increased risk of death as a result of renal disease, cancer, respiratory infections, and other infective and inflammatory causes 21 . Although optimal blood glucose control has been shown to reduce the risk of both macrovascular and microvascular complications 6 , the marked prevalence of renal dysfunction in Asia reflects, in part, the continuing challenge in achieving this goal 22 . The aim of the present article was to review the barriers to achieving optimal blood glucose control in Asian patients with type 2 diabetes who have declining renal function and to discuss the treatment modalities that might be appropriate for the management of these special patient populations.…”
mentioning
confidence: 99%