Wearable biomedical sensors have enabled noninvasive
and continuous
physiological monitoring for daily health management and early detection
of chronic diseases. Among biomedical sensors, wearable pH sensors
attracted significant interest, as pH influences most biological reactions.
However, conformable pH sensors that have sweat absorption ability,
are self-adhesive to the skin, and are gas permeable remain largely
unexplored. In this study, we present a pioneering approach to this
problem by developing a Janus membrane-based pH sensor with self-adhesiveness
on the skin. The sensor is composed of a hydrophobic polyurethane–polydimethylsiloxane
porous hundreds nanometer-thick substrate and a hydrophilic poly(vinyl
alcohol)–poly(acrylic acid) porous nanofiber layer. This Janus
membrane exhibits a thickness of around 10 μm, providing a conformable
adhesion to the skin. The simultaneous realization of solution absorption,
gas permeability, and self-adhesiveness makes it suitable for long-term
continuous monitoring without compromising the comfort of the wearer.
The pH sensor was tested successfully for continuous monitoring for
7.5 h, demonstrating its potential for stable analysis of skin health
conditions. The Janus membrane-based pH sensor holds significant promise
for comprehensive skin health monitoring and wearable biomedical applications.