An alternate route to substituted 6,7-dihydro 5H-dibenz[c,e]azepines from allylbenzamides derived from the Morita–Baylis–Hillman adducts

Palladium-Catalyzed Regiocontrolled Domino Synthesis of N-Sulfonyl Dihydrophenanthridines and Dihydrodibenzo[c,e]azepines: Control over the Formation of Biaryl Sultams in the Intramolecular Direct Arylation

“…During the course of our current investigation, we also uncovered that the protocol described herein could be extended to the synthesis of 6,7-dihydro-5 H -dibenzo[ c , e ]azepines. While the several elegant syntheses of dibenzo[ c , e ]azepines have been reported, to the best of our knowledge, a domino synthesis is unprecedented. When N -Ts benzylamine 51 was subjected to reaction with 6 under the optimized condition, dibenzoazepine 52 and biaryl sultam 53 were obtained in 42 and 53% yields, respectively (Table ).…”

The chemistry of the carbon-transition metal double and triple bond: Annual survey covering the year 2014

“…244) [633], gold dithiocarbamate complexes (e.g. 245) [634], iminosugars [635], a benzpyrroloazepine derivative [636], and swainsonine [637]; (2) an α,β-unsaturated five-membered ring lactam for total synthesis of lundurines A and B (e.g. 246) [638]; (3) five-and six-membered ring lactams that contain fluorinated alkene groups [639]; (4) five-and six-membered ring unsaturated lactams for total syntheses of indolizidinone and quinolizidinone derivatives [640]; (5) five-and six-membered ring amines for preparation of cyclic α-amino acid derivatives [641]; (6) tetrahydropyridines [642,643], including those employed in total syntheses of meloscine analogs (e.g.…”