“…In this paper, using [2], we generalize the ADI OSC method in [8,9] to solve problems that arise when the region is not fixed but evolves in time. The initial-boundary value problem modeling this behavior takes the form (see [10][11][12][13][14][15][16][17][18][19]26]) ∂u ∂t − D u + (∇ · a)u + (a · ∇)u = f(u), (x, y, t) ∈ t × [0, T ], (1.4) n 1 ∂u ∂x + n 2 ∂u ∂ y = 0, (x, y, t) ∈ ∂ t × (0, T ], (1.5) u(x, y, 0) = g(x, y), (x, y) ∈ 0 ∪ ∂ 0 , (1.6) where ∇ ≡ [∂/∂x, ∂/∂ y] T is the gradient operator, a = [a 1 (x, y, t), a 2 (x, y, t)] T is a given vector field, · denotes the standard inner product in R 2 , t ⊂ R 2 is a time-dependent domain with boundary ∂ t and n 1 (x, y, t), n 2 (x, y, t) are the elements of an outward/inward normal vector on the boundary ∂ t .…”