In the context of hydrological model calibration, observational data play a central role in refining and evaluating model performance and uncertainty. Among the critical factors, the length of the data records and the associated climatic conditions are paramount. While there is ample research on data record length selection, the same cannot be said for the selection of data types, particularly when it comes to choosing the climatic conditions for calibration. Conceptual hydrological models inherently simplify the representation of hydrological processes, which can lead to structural limitations, which is particularly evident under specific climatic conditions. In this study, we explore the impact of climatic conditions during the calibration period on model predictive performance and uncertainty. We categorize the inflow data from AnDong Dam and HapCheon Dam in southeastern South Korea from 2001 to 2021 into four climatic conditions (dry years, normal years, wet years, and mixed years) based on the Budyko dryness index. We then use data from periods within the same climatic category to calibrate the hydrological model. Subsequently, we analyze the model’s performance and posterior distribution under various climatic conditions during validation periods. Our findings underscore the substantial influence of the climatic conditions during the calibration period on model performance and uncertainty. We discover that when calibrating the hydrological model using data from periods with wet climatic conditions, achieving comparable predictive performance in validation periods with different climatic conditions remains challenging, even when the calibration period exhibits excellent model performance. Furthermore, when considering model parameters and predicted streamflow uncertainty, it is advantageous to calibrate the hydrological model under dry climatic conditions to achieve more robust results.