An amperometric microsensor array with 1024 individually addressable elements for two-dimensional concentration mapping

Hermes, T.; Bühner, M.; Bücher, S.; Sundermeier, C.; Dumschat, C.; Borchardt, M.; Cammann, Karl; Knoll, Meinhard

doi:10.1016/0925-4005(93)01209-m

Cited by 31 publications

(12 citation statements)

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“…More recently multichannel sensors have been introduced to improve the capability of sensing systems [4]. This way, either the simultaneous measurement of multiple parameters [5] or the introduction of imaging capability has been achieved [6,7]. …”

Section: Introductionmentioning

confidence: 99%

Planar Array Sensor for High-speed Component Distribution Imaging in Fluid Flow Applications

Silva

Sühnel

Schleicher

et al. 2007

Sensors

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A novel planar array sensor based on electrical conductivity measurements is presented which may be applied to visualize surface fluid distributions. The sensor is manufactured using printed-circuit board fabrication technology and comprises of 64 × 64 interdigital sensing structures. An associated electronics measures the electrical conductivity of the fluid over each individual sensing structure in a multiplexed manner by applying a bipolar excitation voltage and by measuring the electrical current flowing from a driver electrode to a sensing electrode. After interrogating all sensing structures, a two-dimensional image of the conductivity distribution over a surface is obtained which in turn represents fluid distributions over sensor's surface. The employed electronics can acquire up to 2500 frames per second thus being able to monitor fast transient phenomena. The system has been evaluated regarding measurement accuracy and depth sensitivity. Furthermore, the application of the sensor in the investigation of two different flow applications is presented.

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Section: Introductionmentioning

confidence: 99%

Planar Array Sensor for High-speed Component Distribution Imaging in Fluid Flow Applications

Silva

Sühnel

Schleicher

et al. 2007

Sensors

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“…Registration of oxygen dynamics of living cells is important for the understanding of cellular metabolism. A common approach to monitor the consumption of oxygen by cells amperometrically is by the use of fiber based electrodes [100 -102], however, a few reports have addressed construction of microchip-based amperometric oxygen sensors intended for cell analysis [99,103]. Saito et al [104] proposed a system composed of a PDMS microchannel in combination with SECM to monitor oxygen consumption by E. coli bacteria.…”

Section: Sensors For Metabolic Activitymentioning

confidence: 99%

Chip Based Electroanalytical Systems for Cell Analysis

et al. 2008

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This review with 239 references has as its aim to give the reader an introduction to the kinds of methods used for developing microchip based electrode systems as well as to cover the existing literature on electroanalytical systems where microchips play a crucial role for nondestructive measurements of processes related to living cells, i.e., systems without lysing the cells. The focus is on chip based amperometric and impedimetric cell analysis systems where measurements utilizing solely carbon fiber microelectrodes (CFME) and other nonchip electrode formats, such as CFME for exocytosis studies and scanning electrochemical microscopy (SECM) studies of living cells have been omitted. Included is also a discussion about some future and emerging nano tools and considerations that might have an impact on the future of "nondestructive" chip based electroanalysis of living cells.

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“…(presumably the target analyte), and the mass-transport mechanisms in the analyte phase (9,11,(34)(35)(36). Amperometry, a special case of voltammetry wherein the potential is kept constant as a function of time, is even more frequently applied in chemical sensors (11,34,35,37) and also provides a linear current-analyte concentration relationship. The constant potential is then predefined by the nature or the redox potential of the target analyte (9,11,34).…”

Section: R Ementioning

confidence: 99%

Adaptive Microsensor Systems

Gutierrez‐Osuna

Hierlemann

2010

Annual Rev. Anal. Chem.

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We provide a broad review of approaches for developing chemosensor systems whose operating parameters can adapt in response to environmental changes or application needs. Adaptation may take place at the instrumentation level (e.g., tunable sensors) and at the data-analysis level (e.g., adaptive classifiers). We discuss several strategies that provide tunability at the device level: modulation of internal sensing parameters, such as frequencies and operation voltages; variation of external parameters, such as exposure times and catalysts; and development of compact microanalysis systems with multiple tuning options. At the data-analysis level, we consider adaptive filters for change, interference, and drift rejection; pattern classifiers that can adapt to changes in the statistical properties of training data; and active-sensing techniques that can tune sensing parameters in real time. We conclude with a discussion of future opportunities for adaptive sensing in wireless distributed sensor systems.

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An amperometric microsensor array with 1024 individually addressable elements for two-dimensional concentration mapping

Cited by 31 publications

References 1 publication

Planar Array Sensor for High-speed Component Distribution Imaging in Fluid Flow Applications

Planar Array Sensor for High-speed Component Distribution Imaging in Fluid Flow Applications

Chip Based Electroanalytical Systems for Cell Analysis

Adaptive Microsensor Systems

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