“…Methohexitone has been used quite extensively as a sole anaesthetic agent by intermittent injection and by infusion for such procedures as tonsillectomy in children (Liscombe, 1968), conservative dentistry (Mann et al, 1971) and bronchoscopy (Hargrove and Pearce, 1964;Mclntosh et al, 1979) and also to supplement nitrous oxide anaesthesia (Hunter, 1972;Prys-Roberts et al, 1983). Earlier investigations on blood concentrations were unable to explain the more rapid recovery following methohexitone than following thiopentone (Sunshine et al, 1966), but the development of more sensitive assay techniques showed that the elimination half-life of methohexitone was relatively short (Breimer, 1976).…”