An Analysis of a Compact Label-Free Guiding-Wave Biosensor Based on a Semiconductor-Clad Dielectric Strip Waveguide

Abstract

In this paper, a compact, integrated, semiconductor-clad strip waveguide label-free biosensor is proposed and analyzed. The device is based on CMOS-compatible materials such as amorphous-Si and silicon oxynitride. The optical sensor performance has been modeled by a three-dimensional beam propagation method. The simulations indicate that a 20-μm-long device can exhibit a surface limit of detection of 3 ng/cm2 for avidin molecules in aqueous solution. The sensor performance compares well to those displayed by other photonic biosensors with much larger footprints. The fabrication tolerances have been also studied in order to analyze the feasibility of the practical implementation of the biosensor.

Complete Single Mode Condition for Silica-Titania Rib Waveguides on Glass Substrates

“…They are a part of many planar integrated circuit (PIC) designs. Single mode propagation is favorable, or even necessary, considering devices that are designed for application in integrated optic telecommunication systems, [5,6] quantum communication applications [7] and integrated optic chemical and biochemical sensor systems [8][9][10], especially those which use the evanescent wave spectroscopy technique [11,12]. Limiting our attention to devices belonging to the second group, it is interesting to note that rib waveguides are being used two different ways.…”

GaN-Based High-Contrast Grating for Refractive Index Sensor Operating Blue–Violet Wavelength Region

“…A sensing techniques of refractive index (RI) have an important contribution for development of the internet of things (IoT) society, such as engineering, biology, and chemical science [ 1 , 2 , 3 ]. In particular, the highly sensitive RI sensors which can operate in aqueous possess large benefits because the RI sensing applications are frequently used in aqueous ambient, such as, immunosensor [ 4 ], blood cell mapping [ 5 ], label-free bio-imaging [ 6 ], and disease-detections [ 7 ]. The RI sensing applications require high sensitivity with compact optical system and high chemical stability (for example, resistance to oxidation).…”