Source-to-sink studies typically utilize the sedimentary record preserved in basins to infer source area parameters such as estimates of drainage area and discharges of fluvial systems in the hinterland, the characterization of which remains elusive as few geomorphic elements of the hinterland are preserved. Clastic wedges within foreland basin settings often contain fluvial deposits, and the scale of fluvial architectural elements can be used to estimate drainage area and discharge within the accreted hinterland. This study uses thicknesses of fluvial architectural elements within the Late Ordovician Taconic, the Late Devonian-Early Mississippian Acadian, and the Late Mississippian to Early and Middle Pennsylvanian Alleghanian clastic wedges, together with climatic conditions interpreted from palaeosol data, to estimate the drainage areas and discharges of the river systems which drained the hinterlands of the accreted Taconic and Acadian terrains and the Alleghanian suture of Laurentia and Gondwana. Published detrital zircon age spectra provide insight into ages of source areas of sediments as well as the timing of terrane accretion. The increase in hinterland drainage areas calculated for Late Devonian Acadian Orogeny river systems compared to Late Ordovician Taconic Orogeny river systems can be attributed to the increase in size of accreted terranes to the east of the foreland basins during that period of time. The decrease in hinterland drainage area from the Late Devonian Acadian Orogeny to the Middle to Late Pennsylvanian Alleghanian Orogeny is attributed to the westward migration of the drainage divide as the Alleghanian orogeny proceeded. It is inferred that the drainage divide migrated towards the drier leeward side of the mountain range and caused drainage basins to shrink and split into smaller drainage basins.