An Analysis of Clinical Profile and Investigations of the Liver Metastasis From Various Gastrointestinal Malignancies

Abstract

BACKGROUND Metastatic malignant tumours of the Liver are common in clinical practice, ranking second only to cirrhosis as a cause of fatal liver disease. At autopsy, 30-50% of all patients dying from malignant diseases reveal hepatic secondaries. MATERIALS AND METHODS Liver metastases are 7 times commoner due to gastrointestinal primary cancers than other tumours. Patients with Liver metastasis due to GI Tract malignancies included in this study, so extra gastrointestinal causes have been excluded from this study. RESULTS 60% of liver metastases in this study is secondary to colorectal primary cancers. 96% of liver metastases are Adenocarcinomatous origin form GI tract. 2% i.e., one case of squamous cell carcinoma of oesophagus and 2% i.e., one case of NHL from small intestine. Female sex predominates as 60% of overall cases with liver secondaries. Average duration of illness before presentation and diagnosis is more in females than males. 96% of these metastases are exclusively from adenocarcinomas. CONCLUSION The surgical management of patients with hepatic metastases involves sorting through many variables and choosing an optimal course of action and utilizing technological advances which will continue to improve the outcome for these unfortunate patients with previously hopeless condition