An analysis of risk factors for pancreatic fistula after pancreaticoduodenectomy: clinical impact of bile juice infection on day 1

Abstract

Bile juice infection on day 1 was a significant risk factor for grade B or grade C POPF after pancreaticoduodenectomy. Although the performance or the status of biliary drainage itself was not a risk factor for POPF, percutaneous biliary drainage might be advantageous against retrograde drainage to reduce the risk of biliary infection.

Analysis of Risk Factors for Delayed Gastric Emptying (DGE) after 387 Pancreaticoduodenectomies with Usage of 70 Stapled Reconstructions

“…This finding is supported by those of other reports, 31,39 but the underling pathogenesis remains unclear. In our institute, POPF was more frequent in men than in women, 38 which could be attributed to the increased incidence of DGE in men.…”

Impact of bacterial contamination of the abdominal cavity during pancreaticoduodenectomy on surgical-site infection

“…Jagannath and co‐workers reported that a positive intraoperative bile culture was associated with infectious complications. In this context, it has been reported that PTBD may reduce the risk of biliary infection. However, PTBD catheter‐tract cancer recurrence was detected in 5·2 per cent of patients with cholangiocarcinoma undergoing resection, suggesting that PTBD should be avoided.…”

Indicators for proper management of surgical drains following pancreaticoduodenectomy

“…These risk factors can be classified into three categories: patient-related factors, pancreatic anatomy, and surgical techniques. Patient-related factors include age, gender, body mass index, visceral fat area, preoperative biliary drainage, and associated co-morbidities [1][2][3][4][5][6][7][8]. Factors related to pancreatic anatomy include soft pancreatic texture, small diameter of the pancreatic duct, fatty pancreas, and postoperative pancreatitis [3,[8][9][10][11][12][13].…”