An analysis of the prevalence of peripheral giant cell granuloma and pyogenic granuloma in relation to a dental implant

Abstract

Background The aim of the present investigation was to evaluate the literature recurrence of peripheral giant cell granuloma and pyogenic granuloma associated with dental implants. It’s important to know the characteristics present in these lesions and possible effects on the prognosis of dental implants. Methods An electronic search without time restrictions was done in the databases: PubMed/Medline. With the keywords "Granuloma" OR "Granuloma, Giant Cell" OR "peripheral giant cell" OR "Granuloma, Pyogenic” AND "Dental implants" OR "Oral implants”. Results After applying the inclusion and exclusion criteria, a total of 20 articles were included, which reported 32 lesions (10 pyogenic granulomas, 21 peripheral giant cell granulomas and one peripheral giant cell granuloma combined with peripheral ossifying fibroma, all associated with implants). According to our review, these lesions are more frequent in males and in the posterior region of the mandible. Both excision and curettage of the lesion, compared to only excision, presented similar recurrences (40%). Explantation of the implant was performed in 41% of cases without additional recurrences. The results are not statistically significant when comparing one lesion to the other in terms of explantation (p = 0.97), recurrence (p = 0.57) or bone loss (p = 0.67). Conclusions The main therapeutic approach is tissue excision. The lesions show a high recurrence rate (34.4%), which often requires explantation of the associated implant. This recurrence rate is not affected by curettage after excision.

Peripheral giant cell granuloma associated with dental implants: Case‐series

“…In the present literature, the association between dental implants and PGCG was not well documented due to the low number of cases reported 4 . A total of 79 cases have reported in the English literature, the largest case series included 20 cases 3,6–11 …”

“…4 A total of 79 cases have reported in the English literature, the largest case series included 20 cases. 3,[6][7][8][9][10][11] The present study represents the largest case series in the literature as yet and was performed in a pathology laboratory dedicated only to oral pathology and a medical center with an oral pathologist on board (Ilana Kaplan). Results of the study indicate that among periimplant lesions biopsied and submitted for analysis, PGCG is not rare, with a prevalence of 15.5% of all peri-implant lesions biopsied.…”

Pyogenic Granuloma: A Literature Review and A Case Report

“…PG associated with implants is more frequent in men, and associated with the posterior regions of the jaws, mainly the mandible. All of them connected with lower levels of oral hygiene and plaque control [17].…”

10,600 nm High Level-Laser Therapy Dosimetry in Management of Unresponsive Persistent Peripheral Giant Cell Granuloma to Standard Surgical Approach: A Case Report with 6-Month Follow-Up

“…Several clinical studies have employed surgical laser (HLLT), including diodes [16][17][18][19], carbon dioxide laser (CO 2 ) [20][21][22][23][24], and the Erbium family (Er:YAG and Er,Cr:YSGG) [25][26][27][28], for a variety of indications due to their bactericidal and regenerative properties [29], but the evidence is scant in relation to PGCG management [17,28] especially for the persistent and rapid eruption type of lesion. Moreover, in terms of the complete healing time, there is a debate in the literature between conventional treatment modalities and surgical laser treatments of various wavelengths (HLLT).…”