An antifungal chromene from Eupatorium riparium

Bandara, B. M. Ratnayake; Hewage, Chandralal M.; Karunaratne, Veranja; Wannigama, G. P.; Adikaram, N. K. B.

doi:10.1016/0031-9422(92)80345-f

Cited by 26 publications

(9 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Root extracts of E. riparium exhibited antifungal activity against Cladosporium cladosporiodes. The active constituent appeared to be methylripariochromene A (6acetyl-7,8-dimethoxy-2,2-dimethylchromene; Bandara et al, 1992).…”

Section: Bioactive Constituentsmentioning

confidence: 99%

A review of the toxicosis and biological properties of the genus Eupatorium

et al. 1998

View full text Add to dashboard Cite

Eupatorium genus grows wild in many parts of the world. A number of species of Eupatorium are toxic to grazing animals. Milk sickness in humans is caused by ingestion of milk of the animals reared on the pastures infested with Eupatorium rugosum (white snakeroot). While some information is available on the toxins in various species of Eupatorium, ambiguities still persist in extrapolation of the data to field incidence of toxicosis. Eupatorium genus has been used for its medicinal properties for many decades. A number of bioactive natural products have been reported in the extracts of Eupatorium spp. and the genus is a promising bioresource for preparation of drugs and value-added products.

show abstract

Section: Bioactive Constituentsmentioning

confidence: 99%

A review of the toxicosis and biological properties of the genus Eupatorium

et al. 1998

View full text Add to dashboard Cite

show abstract

“…Several studies have demonstrated the insecticidal, antibacterial, fungicidal and cytotoxic activities of these substances (Bandara et al, 1992;Burkhardt et al, 1994;Iqbal et al, 2004;Chen et al, 2005). Furthermore, some compounds of this class of natural products have been described to have notable antiprotozoal effect (Alizadeh et al, 2008;Batista Jr. et al, 2008;Harel et al, 2011).…”

Section: Introductionmentioning

confidence: 98%

Chromenes from leaves of Calea pinnatifida and evaluation of their leishmanicidal activity

Lima

Santos

Costa

et al. 2015

Revista Brasileira de Farmacognosia

View full text Add to dashboard Cite

BJP 88 1-4 Revista Brasileira de Farmacognosia xxx (2015) xxx-xxx w w w . s b f g n o s i a . o r g . b r / r e v i s t a a b s t r a c t Calea pinnatifida (R. Br.) Less., Asteraceae, is popularly known as "quebra-tudo", "cipó-cruz" or "aruca". This species is used in the folk medicine for the treatment of stomach pain, giardiasis and amoebiasis. The aim of this study was to isolate and identify chromenes from leaves of C. pinnatifida and evaluate their leishmanicidal activity. A fraction from leaves of C. pinnatifida was analyzed for their chemical constituents, resulting in the isolation and characterization of four known chromenes: 6-acetyl-7-hydroxy-2,2-dimethylchromene (1), 6-acetyl-7-methoxy-2,2-dimethylchromene (2), 6-(1-hydroxyethyl)-7-methoxy-2,2-dimethylchromene (3) and 6-(1-ethoxyethyl)-7-methoxy-2,2-dimethylchromene (4). Structure identification of isolated compounds involved analysis of spectral data of 1D and 2D-NMR. The isolated compounds are here reported for the first time in C. pinnatifida, and the chromenes 1 and 3 show a moderate leishmanicidal activity.

show abstract

“…[3][4][5][6][7] Previous phytochemical studies of Eupatorium species resulted in the isolation of numerous classes of secondary metabolites. 3,4,[8][9][10][11] However, the most characteristic compounds are the sesquiterpene lactones. 11,12 A survey in the literature revealed that the volatile oils from 18 Eupatorium spp.…”

Section: Introductionmentioning

confidence: 99%

“…3,4,[8][9][10][11] However, the most characteristic compounds are the sesquiterpene lactones. 11,12 A survey in the literature revealed that the volatile oils from 18 Eupatorium spp. have been previously analyzed by GC-MS: 10 1 and E. laevigatum from Rio Grande do Sul (south of Brazil) [laevigatin (15.1%), β-caryophyllene (9.6%) and γ -elemene (9.5%) ], there is just laevigatin, the genus chemomarker, in common.…”

Section: Introductionmentioning

confidence: 99%