An antimalarial constituent from alkaloid medang lendir (Litsea glutinosa (Lour.) C. B. Rob)

Lestari, Yuni; Yuanmizesfi, Enggo; Zamri, Adel; Teruna, Hilwan Yuda

doi:10.1063/5.0060175

Cited by 1 publication

(1 citation statement)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In some areas, people use this plant as a mosquito repellent. It was reported that a secondary metabolite from its stem bark possessed an anti-plasmodial activity (Lestari et al, 2021).…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activities of medang lendir (Litsea glutinosa) stem bark

et al. 2023

View full text Add to dashboard Cite

Background: Medang lendir (Litsea glutinosa), a member of the Lauraceae family, is typically found in the Kampar Regency area of Riau Province, Indonesia. This plant is frequently used in traditional medicine to treat rheumatism, diarrhea, and dysentery. Objective: To evaluate the antioxidant activities of L. glutinosa stem bark extracts. Method: L. glutinosa stem bark was macerated in methanol to obtain methanol extract, followed by partitioning with ethyl acetate to obtain ethyl acetate extract. The antioxidant activities of these extracts were determined using the NO radical scavenging and the DPPH radical scavenging methods. The Folin-Ciocalteu method was also used in this study to determine total phenolic content (TPC). Result: The antioxidant activities of ethyl acetate and methanol extracts of L. glutinosa stem bark against NO radicals resulted in a small percentage of inhibition (%I < 0). Meanwhile, for DPPH radical scavenging, the antioxidant activity of the ethyl acetate extract (IC50 = 222.03 ug/mL) was greater than the methanol extract (IC50 = 232.81 ug/mL), and the TPC value of the ethyl acetate extract (23.88 mgGAE/g) was greater than the methanol extract (23.16 mgGAE/g). Conclusion: These results show that the antioxidant activity based on scavenging DPPH radicals for both extracts was active; however, it was inactive on NO radicals. The ethyl acetate extract possessed a higher TPC value compared to the methanol extract.

show abstract

“…In some areas, people use this plant as a mosquito repellent. It was reported that a secondary metabolite from its stem bark possessed an anti-plasmodial activity (Lestari et al, 2021).…”

Section: Introductionmentioning

confidence: 99%