In this paper, invariant difference schemes for nonstationary equations under independent variables transformation constructed and investigated. Under invariance of difference scheme we mean its ability to preserve basic properties (stability, approximation, convergency, etc.) in various coordinate systems. Difference schemes of the second-order approximation that satisfy the invariance property are constructed for equations of parabolic type. Stability and convergency investigation of correspondent difference problems are carried out; a priori estimates in various grid norms are obtained.