Patterns of erosion and deposition act as a filter that strongly influences the disposition of the archaeological record of the Central and Eastern Plains of the North American Midcontinent. Detailed studies of alluvial valley stratigraphy in four drainage basins in the region reveal temporal and spatial patterns of fluvial system behavior that control the preservation and visibility of past human activity. These basins are located on a 600‐km‐long longitudinal gradient extending from semiarid southwestern Kansas to moist‐subhumid central Iowa. Despite significant environmental variability along this transect, basin‐wide patterns of Holocene erosion and deposition are similar across the study area. From ca. 11,000 to 8000 yr B.P., aggradation, punctuated by slow alluviation and/or stability around 10,000 yr B.P., was the dominant process in large and some small valleys. The early and middle Holocene (ca. 8000–5000 yr B.P.) was a period of net erosion and sediment movement in small valleys, sediment storage in large valleys, and episodic aggradation on alluvial fans. During the late Holocene (post‐5000 yr B.P.), alluvial fans stabilized, small valleys became zones of net sediment storage, and aggradation slowed in large valleys. Basin‐wide aggradation followed by entrenchment and channel migration characterizes fluvial activity during the Historic period. Consideration of the effects of these temporal and spatial patterns of Holocene erosion and alluviation on the archaeological record is crucial for developing efficient cultural resource sampling strategies and for accurately interpreting the archaeological record. © 2002 John Wiley & Sons, Inc.