In this paper, we propose a novel hardened latch to mitigate the SEU. The combination of the circuit structure and layout placement is adopted to enhance the multiple nodes upset tolerance. This latch consists of a normal D latch and a typical DICE latch. Different from the TMR latch, this latch can mitigate the charge collection on two transistors. HSPICE simulation results present that there only exit four sensitive transistor pairs in this latch. Compared to the typical DICE and DMR latch, the sensitive transistor pairs are largely reduced. And by adjusting the layout placement, these sensitive transistor pairs are separated from each other as much as possible. From the view of the layout, it is almost impossible for charge collection on the sensitive transistor pairs in our proposed latch.