“…Within AI, ML utilizes a set of inputs and outputs to create an algorithm to process the data and correctly predict the output [ 19 ]. AI and ML have been utilized for several tasks in orthodontics, such as for automated cephalometric analyses [ 20 , 21 , 22 , 23 , 24 ], predicting extraction vs. non-extraction treatment decisions [ 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 ], predicting orthodontic extraction patterns [ 34 ], determining the need for surgery in Class III patients [ 35 ], and growth assessment [ 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 ]. However, little research has been conducted on the use of AI to predict mandibular growth.…”