An assessment of drinking water contamination with <i>Helicobacter pylori</i> in Lima, Peru

Boehnke, Kevin F.; Brewster, Rebecca K.; Sánchez, Brisa N.; Valdivieso, Manuel; Bussalleu, Alejandro; Guevara, Magaly; Saenz, Claudia Gonzales; Alva, Soledad Osorio; Gilman, Elena; Xi, Chuanwu

doi:10.1111/hel.12462

Cited by 28 publications

(21 citation statements)

References 48 publications

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“…A study from Peru added to the previously available evidence that H. pylori DNA can be identified in drinking water samples; 20.3% of drinking water samples were found to be contaminated in the Lince district of Lima. Links were found between lower temperatures and a lower likelihood of the presence of H. pylori , as well as between higher pH and higher quantities of H. pylori .…”

Section: Factors Associated With Helicobacter Pylori Infectionmentioning

confidence: 99%

Epidemiology of Helicobacter pylori infection

et al. 2018

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This review provides the most recent data concerning the epidemiology of Helicobacter pylori infection. Overall, the trend of declining prevalence of H. pylori infection is continuing, with major evidence available from studies in Europe. However, in some parts of the world, for example, in some countries in the Middle East, the prevalence has remained relatively stable. A number of systematic reviews and meta-analyses have been published during the past year indicating the lowest prevalence rates of the infection in Oceania (24.4%), the highest in Africa (79.1%), and the global annual recurrence rate of H. pylori (4.3%). The recurrence rates were found to be directly related to the human development index and prevalence of infection. Several studies have addressed the correlation between H. pylori infection and sociodemographic conditions, source of drinking water and dietary factors. A hypothesis on the role of insects and yeasts in transmitting H. pylori has been suggested and addressed. Helicobacter sp. have been found in flow flies in Brazil. So far there is no evidence available that H. pylori may survive and persist on the outer body of the fly.

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Section: Factors Associated With Helicobacter Pylori Infectionmentioning

confidence: 99%

Epidemiology of Helicobacter pylori infection

et al. 2018

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“…Other possible routes of transmission have been reported. In Peru, H pylori DNA was identified in drink water samples . Likewise, in Brazil, Junqueira et al hypothesized that domestic insects, such as flies, may be related to the transmission of H pylori , due to their feeding and reproduction in fecal material .…”

Section: Introductionmentioning

confidence: 99%

“…In Peru, H pylori DNA was identified in drink water samples. 12 Likewise, in Brazil, Junqueira et al hypothesized that domestic insects, such as flies, may be related to the transmission of H pylori, due to their feeding and reproduction in fecal material. 13 Intrafamilial transmission is considered the main means of H pylori acquisition during early childhood.…”

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Relationship between African Biogeographical Ancestry and Helicobacter pylori infection in children of a large Latin American urban center

et al. 2019

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Background and Aim The relationship between race/ethnicity and H pylori infection has been extensively reported, with a higher prevalence of infection observed in black individuals. Whether such differences are due to genetic factors underlying African ancestry remains to be clarified. In the present study, we evaluated the association between the proportion of individual African ancestry and H pylori infection in a sample of 1046 children living in a large Latin American urban center. Materials and Methods Estimation of individual biogeographical ancestry was based on 370,539 SNPs and performed using the ADMIXTURE software. Multivariate logistic regression models and mediation analysis considering the influence of previously recognized socioenvironmental risk factors to H pylori infection were performed. All analyses were conducted using the statistical package STATA v.14.0. Results Each 10% increase in the proportion of individual African ancestry was positively and independently associated with H pylori infection in our population (adjusted OR = 1.22, 95% CI = 1.10‐1.36, P < .001). Mediation analysis demonstrated that only 9.23% of the effect of the individual African ancestry on H pylori infection was explained by factors such as household income, the absence of street paving and crowding. Conclusions The results suggest that genetic variants that covariate with African ancestry may explain an important part of the racial differences observed for the prevalence of H pylori infection.

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“…Traditionally, culture techniques have been commonly used to enumerate E coli and total coliforms in raw and drinking water . However, some authors have pointed out that some pathogens, such as H pylori , can be able to survive when these indicators are inactivated . Thus, the enumeration of coliform bacteria as indicators of drinking water quality may not correlate accurately with the risk this water possesses to consumers .…”

Section: Introductionmentioning

confidence: 99%

“…30,31 However, some authors have pointed out that some pathogens, such as H pylori, can be able to survive when these indicators are inactivated. 5,32,33 Thus, the enumeration of coliform bacteria as indicators of drinking water quality may not correlate accurately with the risk this water possesses to consumers. 27,32,34 There are few studies that look for indicator microorganisms different from the traditional ones to monitor water quality.…”

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confidence: 99%

Correlation among fecal indicator bacteria and physicochemical parameters with the presence of Helicobacter pylori DNA in raw and drinking water from Bogotá, Colombia

et al. 2019

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Background The quality of raw and drinking water is a matter of considerable concern due to the possibility of fecal contamination. To assess the quality and public health risk of different types of water, the fecal indicator bacteria (FIB) are used. However, some pathogens, such as Helicobacter pylori, may be present in water when FIB cannot be found. H pylori is recognized as the causative agent of chronic gastritis, peptic and duodenal ulcers, and gastric cancer. The aim of this study was to evaluate the relationships among physicochemical parameters, FIB concentrations, and the presence of H pylori DNA in raw and drinking water from Bogotá, Colombia. Materials and Methods A total of 310 water samples were collected 1 day per week from July 2015 to August 2016, and physicochemical parameters (pH, turbidity, conductivity, and residual free chlorine) were measured. Presence of H pylori DNA was determined and quantified by quantitative polymerase chain reaction (qPCR). Fecal indicator bacteria (total coliforms, Escherichia coli, and spores of sulfite‐reducing Clostridia) were enumerated by using standard culture techniques. Results Thirty of 155 (31%) raw water samples and forty‐eight of 155 (38.7%) drinking water samples were positive for the presence of H pylori. No statistically significant relationships were found between physicochemical parameters or FIB with the presence or absence of H pylori in any sample (P < 0.05). Conclusions This study provides evidence of the presence of H pylori DNA in raw and drinking water in Bogotá, and shows that the detection and enumeration of FIB and physicochemical parameters in water do not correlate with the risk of contamination with H pylori.

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An assessment of drinking water contamination with Helicobacter pylori in Lima, Peru

Cited by 28 publications

References 48 publications

Epidemiology of Helicobacter pylori infection

Epidemiology of Helicobacter pylori infection

Relationship between African Biogeographical Ancestry and Helicobacter pylori infection in children of a large Latin American urban center

Correlation among fecal indicator bacteria and physicochemical parameters with the presence of Helicobacter pylori DNA in raw and drinking water from Bogotá, Colombia

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