Lithium-ion batteries (LIBs) have become a hot topic worldwide because they are not only the best alternative for energy storage systems but also have the potential for developing electric vehicles (EVs) that support greenhouse gas (GHG) emissions reduction and pollution prevention in the transport sector. However, the recent increase in EVs has brought about a rise in demand for LIBs, resulting in a substantial number of used LIBs. The end-of-life (EoL) of batteries is related to issues including, for example, direct disposal of toxic pollutants into the air, water, and soil, which threatens organisms in nature and human health. Currently, there is various research on spent LIB recycling and disposal, but there are no international or united standards for LIB waste management. Most countries have used a single or combination methodology of practices; for instance, pyrometallurgy, hydrometallurgy, direct recycling, full or partial combined recycling, and lastly, landfilling for unnecessary waste. However, EoL LIB recycling is not always easy for developing countries due to multiple limitations, which have been problems and challenges from the beginning and may reach into the future. Laos is one such country that might face those challenges and issues in the future due to the increasing trend of EVs. Therefore, this paper intends to provide a future perspective on EoL LIB management from EVs in Laos PDR, and to point out the best approaches for management mechanisms and sustainability without affecting the environment and human health. Significantly, this review compares the current EV LIB management between Laos, neighboring countries, and some developed countries, thereby suggesting appropriate solutions for the future sustainability of spent LIB management in the nation. The Laos government and domestic stakeholders should focus urgently on specific policies and regulations by including the extended producer responsibility (EPR) scheme in enforcement.