Laboratory experiment was conducted to examine sublethal effects of beta-cyfluthrin (Bulldock ® 025 SC) on the sepia mutant of Drosophila melanogaster at a temperature of 25Ϯ0.5°C, 50Ϯ5% relative humidity and a photoperiod of 16 : 8 (light : dark) hours. Males and females were exposed separately to beta-cyfluthrin (one tenth of the calculated LC 50 value) mixed in the diet for 24, 48 and 72 h. Fecundity, hatchability, pupation, adult emergence, larval, pupal and total developmental periods were evaluated in the F 1 generation after various cross combinations. A reduction in fecundity, egg hatching, number of larvae, pupae, adults and prolongation of larval, pupal and total developmental periods was observed. A significant reduction (pϽ0.05) in fecundity was observed only on the treated diet after treatment of both the sexes. Maximum effects were observed after 72 h treatment followed by 48 and 24 h. Males were found to be more susceptible to beta-cyfluthrin as compared to the females.