An assessment of the quality of optical coherence tomography image acquisition

Zago, Elder; Samdani, Abdul Jawwad; Pereira, Gabriel Tensol Rodrigues; Vergara-Martel, Armando; Alaiti, Mohamad Amer; Dallan, Luís Augusto Palma; Pizzato, Patricia; Zimin, Vladislav N.; Fares, Anas; Bezerra, Hiram G.

doi:10.1007/s10554-020-01795-8

Cited by 5 publications

(6 citation statements)

References 28 publications

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“…Although this novel HF-OCT system lays on the same fundamental | 525 than manual injections, also better controlling the amount of contrast medium injected during OCT imaging 25,26 ; therefore, it contributed to the low-contrast OCT image acquisition presented in this study. A 5 mL contrast medium injection is as small as the amount of contrast medium used to image a coronary angiogram.…”

Section: Discussionmentioning

confidence: 99%

“…With this study, we proved the feasibility of a low‐contrast, fast‐pullback, HF‐OCT imaging procedure for coronary lesion assessment using only 5 mL of contrast. The use of automated contrast injectors is known to provide better and more reproducible image quality than manual injections, also better controlling the amount of contrast medium injected during OCT imaging 25,26 ; therefore, it contributed to the low‐contrast OCT image acquisition presented in this study. A 5 mL contrast medium injection is as small as the amount of contrast medium used to image a coronary angiogram.…”

Section: Discussionmentioning

confidence: 99%

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Efficacy of a new generation intracoronary optical coherence tomography imaging system with fast pullback

Nishi

Kume

Yamada

et al. 2023

Cathet Cardio Intervent

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Objectives We sought to investigate whether a novel, fast‐pullback, high‐frequency optical coherence tomography (HF‐OCT) imaging system enables data acquisition with a reduced amount of contrast agents while retaining the same qualitative and quantitative lesion assessment to conventional OCT. Background The increased amount of administered contrast agents is a major concern when performing intracoronary OCT. Methods The present study is a single‐center, prospective, observational study including 10 patients with stable coronary artery disease. A total of 28 individual coronary arteries were assessed by both fast‐pullback HF‐OCT and by conventional OCT. Results The contrast volume used in each OCT run for the HF‐OCT system was significantly lower than for the conventional OCT system (5.0 ± 0.0 mL vs. 7.8 ± 0.7 mL, respectively, with a mean difference of −2.84 [95% confidence interval [CI]: −3.10 to −2.58]). No significant difference was found in the median value of the clear image length between the two OCT systems (74 mm [interquartile range [IQR]; 63, 81], 74 mm [IQR; 71, 75], p = 0.89). Fast‐pullback HF‐OCT showed comparable measurements to conventional OCT, including minimum lumen area (3.27 ± 1.53 mm2 vs. 3.21 ± 1.53 mm2, p = 0.27), proximal reference area (7.03 ± 2.28 mm2 vs. 7.03 ± 2.34 mm2, p = 0.96), and distal reference area (5.93 ± 1.96 mm2 vs. 6.03 ± 2.02 mm2, p = 0.23). Qualitative OCT findings were comparable between the fast‐pullback HF‐OCT runs and conventional OCT with respect to identifying lipid‐rich plaques, calcifications, layered plaques, macrophages, and cholesterol crystals. Conclusion With the fast pullback function of a novel HF‐OCT imaging system, we acquired OCT images using a significantly lower amount of contrast volume while retaining a comparable qualitative and quantitative lesion assessment to conventional OCT.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Efficacy of a new generation intracoronary optical coherence tomography imaging system with fast pullback

Nishi

Kume

Yamada

et al. 2023

Cathet Cardio Intervent

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“…The clear length of the scans expressed in millimeters was measured in all 72 pullbacks acquired automatically (for which the scan acquisition speed is known) using established criteria, known as the CIL ( 49 ). CIL represents the length of the scan without blood shadowing artifacts.…”

Section: Methodsmentioning

confidence: 99%

Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe

Pereira,

Lylyk,

Cancelliere

et al. 2024

Sci. Transl. Med.

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Endovascular interventions are increasingly becoming the preferred approach for treating strokes and cerebral artery diseases. These procedures rely on sophisticated angiographical imaging guidance, which encounters challenges because of limited contrast and spatial resolution. Achieving a more precise visualization of the underlying arterial pathology and neurovascular implants is crucial for accurate procedural decision-making. In a human study involving 32 patients, we introduced the clinical application of a miniaturized endovascular neuro optical coherence tomography ( n OCT) imaging probe. This technology was designed to navigate the tortuous paths of the cerebrovascular circulation and to offer high-resolution imaging in situ. The n OCT probe is compatible with standard neurovascular microcatheters, integrating with the procedural workflow used in clinical routine. Equipped with a miniaturized optical fiber and a distal lens, the probe illuminates the tissue and collects the backscattered, near-infrared light. While rotating the fiber and the lens at high speed, the probe is rapidly retracted, creating a spiral-shaped light pattern to comprehensively capture the arterial wall and implanted devices. Using n OCT, we demonstrated volumetric microscopy of cerebral arteries in patients undergoing endovascular procedures. We imaged the anterior and posterior circulation of the brain, including distal segments of the internal carotid and middle-cerebral arteries, as well as the vertebral, basilar, and posterior cerebral arteries. We captured a broad spectrum of neurovascular pathologies, such as brain aneurysms, ischemic stroke, arterial stenoses, dissections, and intracranial atherosclerotic disease. n OCT offered artifact-free, high-resolution visualizations of intracranial artery pathology and neurovascular devices.

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“…All runs and angiography were then reviewed by two blinded operators (DG and DA). The quality of HF-OCT images was evaluated by clear image length (CIL, mm), defined by a minimum of 270° of the vessel circumferences distinctly discernible ( 15 ). A good-quality image was considered to have a CIL% ≥ 80% ( 15 ).…”

Section: Methodsmentioning

confidence: 99%

Experience with a novel high frequency optical coherence tomography device for intracoronary imaging: a case series

Garin,

Cook,

Togni

et al. 2024

Front. Cardiovasc. Med.

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IntroductionIntravascular imaging, especially optical coherence tomography (OCT), has significantly improved percutaneous coronary intervention (PCI), yet its routine clinical application faces challenges. This case series introduces the Gentuity® High-Frequency Optical Coherence Tomography (HF-OCT), a novel device designed to enhance intracoronary imaging with a significantly faster pullback and smaller catheter size, potentially offering enhanced navigability in complex lesions. We aimed to assess the image quality of Gentuity® HF-OCT in complex vessel conditions, as well as presenting a case series to illustrate the application of the device in various clinical scenarios.MethodsIn this case series, we included all patients who underwent intracoronary HF-OCT imaging at our center. The primary endpoint was image quality assessed by clear image length (CIL). Image quality was assessed in relation to (1) lesion severity assessed by minimum lumen area (MLA); (2) vessel size, differentiating between larger (diameter ≥ 4 mm) and smaller vessel segments; (3) pre- vs. post-PCI conditions, and (4) vessel tortuosity, categorized into none, moderate, and severe.ResultsTwenty-four HF-OCT runs from 14 patients were included. No significant differences in CIL were observed across lesion severity terciles (p = 0.449), between small and large vessel segments [mean CIL% difference 1.3%; confidence interval (CI), −9.3 to 11.8; p = 0.802], and pre- vs. post-PCI conditions (mean CIL difference −3.9 mm; CI, −14.0 to 6.1; p = 0.373). Vessel tortuosity significantly impacted image quality, with clear reductions in CIL observed in cases of moderate (74.8; CI, 73.5 to 76.0; vs. 63.9; CI, 56.2 to 71.5; p = 0.043) and severe tortuosity (74.8; CI, 73.5 to 76.0; vs. 65.0; CI, 62.1 to 67.9; p = 0.002) compared to vessels with no tortuosity. Overall, the HF-OCT demonstrated excellent catheter deliverability and crossability, with very satisfactory image quality and no significant adverse events.ConclusionThe Gentuity® HF-OCT is a new OCT device capable of navigating both small- and large-diameter vessels, with similar image quality, but vessel tortuosity seems to have an impact on image quality. It appears to be as usable as conventional OCT for pre-PCI diagnosis and OCT-guided PCI, potentially bringing additional benefits in terms of deliverability, lesion crossover and ease of use in routine clinical practice.

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An assessment of the quality of optical coherence tomography image acquisition

Cited by 5 publications

References 28 publications

Efficacy of a new generation intracoronary optical coherence tomography imaging system with fast pullback

Efficacy of a new generation intracoronary optical coherence tomography imaging system with fast pullback

Volumetric microscopy of cerebral arteries with a miniaturized optical coherence tomography imaging probe

Experience with a novel high frequency optical coherence tomography device for intracoronary imaging: a case series

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