This study attempted to explore farmers’ adaptation decisions and assess the determinants of these adaptation strategies by using the multivariate probit model. A survey of 350 Vietnamese agricultural households was carried out covering districts with and without national interprovincial road traversing in Northwest and North Central Coast region. Five adaptation practices (new technology application, cropping calendar adjustment, implementation of soil preservation, crops and livestock diversification, and households’ income management) were deemed as outcome variables, and fifteen variables were deployed as explanatory variables. The results indicate a significant difference in the application of agricultural adaptation methods related to the geographical location of provinces in connection with inter-provincial highways. Additionally, perceived risks about existence of climate change, accessibility of microcredit, and temperature, were found to be more influential compared to other factors. All five adaptation options were found to be complimentary to each other. Importantly, the intensity of the impact of dependent variables in different practices, and for the available adaptation options, were found to be unequal. This study, therefore, suggested that policies on adaptation strategies should be taken into consideration while credit for households should be supported and encouraged by the governments and relevant governmental agencies.