An Attempt to Evaluate Antiviral Activity of Plant Extracts to Combat Infections Caused by Viruses Including SARS COV-2.

Tripathi, Ashutosh

doi:10.2139/ssrn.3599444

Cited by 5 publications

(5 citation statements)

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“…Biologically active substances of plant origin have long been recognized as viral inhibitors. These antiviral compounds can be extracted from sources such as higher plants, which, for many reasons, have been discovered much less than the traditional ones [30].…”

Section: Resultsmentioning

confidence: 99%

In-vitro Antiviral Activity of Natural Products against Coronavirus Strains: A Systemic Review

Kc¹,

Pandit²,

Shrivastava³

2020

Preprint

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Coronavirus is a non-segmented, positive-sense RNA genome belonging to the family coronaviridae in the order Nidovirales Corona viral infections have created serious threats in the last couple of decades and recently claiming the death of thousands of human beings. Natural products provide a valuable and powerful resource of chemical compounds alkaloids, tannins, caffeine, biopterin, actinophnine, etc. displaying antiviral properties. The data was reviewed from various databases or search engines: PubMed, Science Direct, MedLine, Google Scholar, and Biomed central for published articles. The data inclusion criteria was natural products and their isolated and different synthetic compounds. Data duplication and titles or contents that do not meet the inclusion criteria and Reports on antiviral activities of natural products or their derivatives against other than CoV strains were excluded. We encountered 49 plants and 19 compound chemically defined natural molecules reported in the literature, which have evaluated for potent antiviral activity against different coronavirus strains. The listed plants and their compounds in this review are highly potent with promising results against coronavirus. These can be further screened for invasive tests and used for making different formulations or may be polyherbal formulations considering its safety profile and toxicity.

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Section: Resultsmentioning

confidence: 99%

In-vitro Antiviral Activity of Natural Products against Coronavirus Strains: A Systemic Review

Kc¹,

Pandit²,

Shrivastava³

2020

Preprint

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show abstract

“…On the other hand, the extract of Neem bark at a variable concentration of 50 to 100 µg / mL can stop the entry of Herpes Virus Simplex (HSV-1) into cells 56 . This plant's use in treating infections of various viruses such as poliovirus, bovine herpesvirus type 1, duck plague virus has also been reported 57 . Molecules present in this plant species, such as Nimbaflavone, rutin, and Hyperoside, have shown a potential inhibition in influenza viruses (H1N1, H1N2, H2N2, H2N3, H5N1, H7N2, H7N3, H7N7, and H9N2) by exhibiting extensive antiviral properties 58 .…”

Section: Azadirachta Indica[a38] a Jussmentioning

confidence: 97%

Potential bioactive compounds of medicinal plants against new Coronavirus (SARS-CoV-2): A review

Manzano

Tivillin

Chóez-Guaranda

et al. 2021

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Nowadays, COVID-19 cases are growing worldwide, and there is no evidence of an effective drug to combat the new SARS-CoV-2 virus. In this sense, medicinal plants as an alternative treatment are being used without control to handle the pandemic situation. Therefore, bioactive compounds against Coronavirus of medicinal plant species that grow in Ecuador are discussed. The plant species described in this review are Azadirachta indica, Cinchona pubescens, Coriandrum sativum, Cúrcuma longa, Eucalyptus spp, Morus alba, and Salvia rosmarinus[A3] ; and compunds are curcumin, coriandrin, deoxynojirimycin, kuwanon G, mulberroside A, oleanolic acid, rosmarinic acid, ursolic acid, quinine, eucalyptol, and jensenone.

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“…Es conocido que las transmisiones de enfermedades infecciosas de origen viral causan una alta tasa de mortalidad a nivel mundial; tanto por la resistencia de distintos virus a medicamentos, como por la aparición de nuevos patógenos que provocan una dificultad en la apropiada terapia a pacientes infectados (Boukhatem & Setzer, 2020). La importancia del uso de sustancias biológicamente activas radica en su reconocimiento como inhibidores virales que son señalados como una alternativa directa a la emergente situación sanitaria (Tripathi et al, 2020).…”

Section: Afectación De Distintos Virus a La Salud Humanaunclassified

Extractos De Plantas Microencapsuladas Con Potencial Actividad Antiviral: Una Revision General

Conterón¹,

Hernández

2022

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El uso de compuestos activos de plantas ha generado una alternativa natural en torno a las afecciones que involucran la salud humana. Un extracto de plantas es una mezcla compleja de moléculas bioactivas que presenta propiedad antioxidante, antiviral, antimicrobiana, antiparasitaria, entre otras. A pesar que un reto prominente para el uso de extractos herbales es el uso de solventes orgánicos pues dificultan su formulación y administración directa a personas, esto podría ser solucionado ya que investigaciones recientes señalan a la microencapsulación como una tecnología alentadora en la administración de fitofármacos. La presente revisión se centró en treinta y dos estudios publicados en idioma Inglés y Español de algunas investigaciones relevantes realizadas mayoritariamente en los últimos diez años que señalaron la importancia de las plantas en el área farmacéutica, principios activos de plantas con actividad antiviral, formulaciones de extractos de plantas, además del uso de la microencapsulación para su presentación final y aseguramiento en su biodisponibilidad, proporcionando una descripción general en la investigación global sobre el secado de extractos herbales con potencial actividad antiviral.

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An Attempt to Evaluate Antiviral Activity of Plant Extracts to Combat Infections Caused by Viruses Including SARS COV-2.

Cited by 5 publications

References 0 publications

In-vitro Antiviral Activity of Natural Products against Coronavirus Strains: A Systemic Review

In-vitro Antiviral Activity of Natural Products against Coronavirus Strains: A Systemic Review

Potential bioactive compounds of medicinal plants against new Coronavirus (SARS-CoV-2): A review

Extractos De Plantas Microencapsuladas Con Potencial Actividad Antiviral: Una Revision General

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