An attentional assessment of foster children at risk for schizophrenia.

Asarnow, Robert F.; Steffy, Richard A.; MacCrimmon, Duncan J.; Cleghorn, John M.

doi:10.1037/0021-843x.86.3.267

Cited by 160 publications

(93 citation statements)

References 8 publications

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“…High-risk studies have reported an increased incidence of neurobehavioral problems in children of schizophrenic parents during late childhood and adolescence when compared to children of mentally healthy parents and children whose parents have other mental disorders, such as depression (Cornblatt and Obuchowski 1997). These neurobehavioral problems include subtle deficits in information processing and attentional functioning (Asarnow et al 1977;Cornblatt et al 1999;Nuechterlein 1985), as well as motor-coordination problems (Erlenmeyer-Kimling et al 2000;Hans et al 1999;Marcus et al 1993;Marcus et al 1985;McNeil and Cantor-Graae 2000). Although most highrisk samples have not been followed through the age of likely onset of schizophrenia, some evidence suggests that neurobehavioral signs during childhood and adolescence may be predictive of the development of schizophrenia (Mirsky et al 1995) and related psychosis (Erlenmeyer-Kimling et al 2000).…”

Section: Introductionmentioning

confidence: 95%

Development from Birth to Adolescence of Children At-Risk for Schizophrenia

Hans

Auerbach²,

Auerbach³

et al. 2005

Journal of Child and Adolescent Psychopharmacology

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Section: Introductionmentioning

confidence: 95%

Development from Birth to Adolescence of Children At-Risk for Schizophrenia

Hans

Auerbach²,

Auerbach³

et al. 2005

Journal of Child and Adolescent Psychopharmacology

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“…Well-known studies of adopted-away offspring of schizophrenic parents (Heston, 1966;Rosenthal et al, 1968) are not included because, starting with adult subjects, they have yielded retrospective, rather than prospective, information about early indicators. The very small sample of fostered-away chidren studied at younger ages by Asarnow, MacCrimmon, Cleghorn, and Steffy (1978) is included, however.…”

Section: Research On Risk Factors For Schizophrenia Is Reviewed With mentioning

confidence: 99%

Biobehavioral risk factors in children of schizophrenic parents

Erlenmeyer‐Kimling

Cornblatt

1984

J Autism Dev Disord

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Research on risk factors for schizophrenia is reviewed with emphasis on children of schizophrenic parents. As children of schizophrenic parents are not representative of the majority of individuals who become schizophrenic, examination of variables such as those relating to home environment or parental characteristics in these children is not expected to contribute greatly to an understanding of risk for schizophrenia or to the search for early indicators of a genetic liability, whereas study of selected biobehavioral variables may do so. Four areas of biobehavioral functioning that have been examined in high-risk research are discussed. Three of these are considered to be compatible with the hypothesis of a neurointegrative defect underlying schizophrenia-proneness and to be promising for further research.

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“…Abnormalities in unaffected relatives are assumed not to be secondary to the effects of having the disorder, but reflect an unexpressed liability to develop schizophrenia. This strategy has been used to identify neurocognitive indices of vulnerability to schizophrenia that are suspected to be under partial genetic control (Asarnow et al, 1977Erlenmeyer-Kimling, 2000;Faraone et al, 1995;Nuechterlein et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

MMPI Vulnerability Indicators for Schizophrenia and Attention Deficit Disorder: UCLA Family Study of Biological Parents of Offspring with Childhood-Onset Schizophrenia or ADHD

et al. 2005

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Minnesota Multiphasic Personality Inventory (MMPI) scores were examined for 50 parents of children with an onset of schizophrenia prior to 14 years of age, 153 parents of children with attention deficit hyperactivity disorder (ADHD), and 168 parents of community comparison children. The parents were participants in the UCLA Family Study. The mean scores on all standard MMPI scales were within normal limits for all three groups of participants. Parents of schizophrenia probands were significantly higher on scale Sc than parents of community comparison children. Previous research has shown that scale Sc may be associated with a genetic liability to developing schizophrenia. Thus, scale Sc shows promise as an indicator of a heightened risk for the development of schizophrenia. The parents of the ADHD probands were significantly higher on standard clinical scale Pd than community comparison parents. Mothers of both schizophrenia and ADHD probands shared some personality indicators of stress reactivity. Although this study, like all non-adoptee family studies, cannot disentangle genetic effects on the development of these personality characteristics from environmental effects, we speculate that the emotional distress resulting in higher levels of the MMPI characteristics seen in the patients' mothers reflects the impact of raising a psychiatrically ill offspring.

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An attentional assessment of foster children at risk for schizophrenia.

Cited by 160 publications

References 8 publications

Development from Birth to Adolescence of Children At-Risk for Schizophrenia

Development from Birth to Adolescence of Children At-Risk for Schizophrenia

Biobehavioral risk factors in children of schizophrenic parents

MMPI Vulnerability Indicators for Schizophrenia and Attention Deficit Disorder: UCLA Family Study of Biological Parents of Offspring with Childhood-Onset Schizophrenia or ADHD

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